Neurotransmitters Flashcards
Difference between neurotransmitter and neuromodulator
Neuromodulator is slower to act because they use GPCR and they have a second messenger system
Neurocrine molecules can be grouped into 7 classes
Acetylcholine, amines, amino acids, peptides, purine, gases and lipids
What is the synthesis of acetylcholine
Choline and acetyl coa
Which type of receptor acetylcholine binds
Cholinergic
cholinergic has 2 main subtypes what is it
Nicotine and muscatinic
Where is nicotinic receptors located
Skeletal muscle and in the autonomic division of PNS and CNS
Where is the muscarinic receptors located
In the CNS and on target cells for automatic parasympathetic division of PNS
What is the types of receptors of nicotinic and muscarinic
Nicotinic is ionogropic receptor ( faster response)
And muscarinic is GPCR
What are the chemicals of amines
Serotonin from tryptophan
Histamine from histamine
Dopamine, norepinephrine and epinephrine from Tyrosine
What is the receptor of norepinephrine and epinephrine
Adrenergic alpha and beta
What is the receptors of histamine
GPCR
Where is located the receptors of norepinephrine and epinephrine
Smooth and cardiac muscle, glands and CNS
Where is located histamine receptors
CNS
What is the chemicals of amino acids
Glutamate , aspartame, gamma aninobutyric acid GABA , glycine and D serine
Is glutamate excitatory or inhibitory
Excitatory and it is found at CNS