Neurotransmitters Flashcards

1
Q

Difference between neurotransmitter and neuromodulator

A

Neuromodulator is slower to act because they use GPCR and they have a second messenger system

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2
Q

Neurocrine molecules can be grouped into 7 classes

A

Acetylcholine, amines, amino acids, peptides, purine, gases and lipids

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3
Q

What is the synthesis of acetylcholine

A

Choline and acetyl coa

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4
Q

Which type of receptor acetylcholine binds

A

Cholinergic

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5
Q

cholinergic has 2 main subtypes what is it

A

Nicotine and muscatinic

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6
Q

Where is nicotinic receptors located

A

Skeletal muscle and in the autonomic division of PNS and CNS

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7
Q

Where is the muscarinic receptors located

A

In the CNS and on target cells for automatic parasympathetic division of PNS

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8
Q

What is the types of receptors of nicotinic and muscarinic

A

Nicotinic is ionogropic receptor ( faster response)
And muscarinic is GPCR

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9
Q

What are the chemicals of amines

A

Serotonin from tryptophan
Histamine from histamine
Dopamine, norepinephrine and epinephrine from Tyrosine

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10
Q

What is the receptor of norepinephrine and epinephrine

A

Adrenergic alpha and beta

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11
Q

What is the receptors of histamine

A

GPCR

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12
Q

Where is located the receptors of norepinephrine and epinephrine

A

Smooth and cardiac muscle, glands and CNS

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13
Q

Where is located histamine receptors

A

CNS

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14
Q

What is the chemicals of amino acids

A

Glutamate , aspartame, gamma aninobutyric acid GABA , glycine and D serine

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15
Q

Is glutamate excitatory or inhibitory

A

Excitatory and it is found at CNS

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16
Q

What are the receptors for glutamate

A

AMOA, NMDS, glutaminergic metabotropic

17
Q

Is aspartate excitatory or inhibitory

A

Excitatory in the brain

18
Q

What is the function of aspartate

A

Depolirizes Target cells

19
Q

Is GABA inhibitory or excitatory

A

Inhibitory

20
Q

What is the function of GABA

A

Hyperpolorizes target cells by opening Cl- gates

21
Q

What is the function of glycine and D serine

A

Enhance the excitatory effect of glutamate