NeuroPsych Flashcards
Neurotransmitter changes in anxiety
H norepi
L serotonin
L GABA
Neurotransmitter changes in depression
L serotonin
L norepi
L dopamine
Neurotransmitter changes in Huntington disease
H dopamine
L acetylcholine
L GABA
Neurotransmitter changes in Parkinson disease
H acetylcholine
L serotonin
L dopamine
Neurotransmitter change in Alzheimer
L acetylcholine
synthesis of norepinephrine
locus ceruleus
synthesis of dopamine
substancia nigra pars compacta
ventral tegmentum
synthesis of serotonin
raphe nucleus
synthesis of acetylcholine
basal nucleus of Meynert
synthesis of GABA
nucleus accumbens
Hypothalamic nucleus affected in Kallman syndrome
Preoptic nucleus
release of GnRH
TRAPS of Parkinson disease
Tremors at rest Rigidity (cogwheel) Akinesia / bradykinesia Postural instability Shuffling gait
EOM during REM sleep is due to
PPRF (paramedian pontine reticular formation) / conjugate gaze center
hyperorality
hypersexuality
disinhibited behavior
Kluver - Bucy syndrome
Gerstmann syndrome results from a lesion in
dominant parieto temporal cortex
s/sx of Wernicke encephalopathy
CAN
Confusion
Ataxia
Nystagmus
hemiballismus results from a lesion in
contralateral subthalamic nucleus
(lacunar stroke)
lesion at the amygdala (bilateral) results in
Kluver - bucy syndrome
lesion at the hippocampus (bilateral) results in
anterograde amnesia
inability to create new memories
common iatrogenic cause of central pontine myelinolysis
overly rapid correction of hyponatremia
bilateral occlusion of ACA can result in
behavioral change (abulia) urinary incontinence
artery involved in medial medullary syndrome
anterior spinal artery
and vertebral artery
artery involved in wallenberg syndrome
PICA
especially affecting the nucleus ambiguus
locked - in syndrome results from a stroke in
basilar artery
lateral pontine syndrome results from a stroke in
AICA
PCOM aneurysm results in
CN III palsy
- eyes down and out
- ptosis
- mydriasis
risk of vasospasm in SAH occurs in
2-3 days
appearance of stroke in MRI and CR
MRI: bright in 3-30 mins (DWI)
CT: dark in 12-24 hours (noncontrast)
aspects of cognition
memory
attention
judgment
language
s/sx of manic episode
“manics DIG FAST”
Distractibility Irresponsibility Grandiosity Flight of ideas Activity increased Sleep less Talkativeness
s/sx of MDD
“SIG E CAPS”
Sleep disturbance Interest loss / anhedonia Guilt / worthlessness Energy loss and fatigue Concentration problems Appetite / wt changes Psychomotor retardation / agitation Suicida ideations
Depressed mood
the disturbance of PTSD lasts
> 1 month
major defense mechanism of paranoid personality disorder
projection
major defense mechanism of borderline personality disorder
splitting
cluster A personality disorders
“weird”
paranoid
schizoid
schizotypal
cluster B personality disorders
“wild”
antisocial
borderline
histrionic
narcissistic
cluster C personality disorders
“worried”
avoidant
OCPD
dependent
ECG waveform with highest frequency and lowest amplitude
Beta
stage of sleep where night terrors usually occur
N3
slow wave sleep
evolution of EPS side effects
“ADAPT”
4h - acute dystonia
4d - akithesia
4w - parkinsonism
4mo - tardive dyskinesia
neuroleptic malignant syndrome s/sx
“FEVER”
Fever Encephalopathy VS unstable Enzymes high (myoglobinuria) Rigidity of muscles