Neuroplasticity Flashcards
Learning
Process by which experiences change the nervous system
Changes referred to as memories
Hebb Rule/ Hebb Synapse
Connection between 2 neurons takes place only if both neurons are firing at the same time
Synaptic Enhancement
After affect of pre synaptic action potential increases the amount of neurotransmitter released by successive action potentials
Post Tetanic Potentiation
Potentiation following a sustained, high frequency burst of action potential
Short Term Synaptic Enhancement
Triggered by buildup of intracellular calcium inside pre synaptic terminal during action potential activity
Long Term Potentiation
Long term changes in synaptic strength
Heterosynaptic- specific to which neurons are activated at the same time
Associative
NMDA Receptors
Calcium ion channel usually blocked by Mg
To turn on NMDA receptor, 2 events must happen at the same time (binds glutamate, removal of Mg)
Presynaptic neuron releases glutamate, Mg removed when post synaptic neurone is depolarized (EPSP)
NMDA Receptors and LTP
Open NMDA receptor channels allow calcium influx, which trigger LTP
Functions of Calcium
Activates nitrous oxide, diffuses to pre synaptic terminal, changes ability of pre synaptic terminal to release glutamate (will release more glutamate in the future)
Increases number and sensitivity of AMPA receptors (glutamate receptors)
Changes size of synapse (bigger- more surface area)