Neuropathaties Flashcards

1
Q

What is a mononeuropathy?

A

Lesion/damage restricted to a single peripheral nerve

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2
Q

Which nerves are commonly affected in a mononeuropathy

A

Ulnar
Radial
Median
Common peroneal

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3
Q

What is carpal tunnel syndrome?

A

Compression of the median nerve in the carpal tunnel

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4
Q

In which conditions does carpal tunnel commonly occur?

A
Pregnancy
Hypothyroid
Acromegaly 
Rh Art
Diabetes
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5
Q

How does carpal tunnel present?

A

Pain and tingling in the hand worse at night
Weakness of thumb abduction
Thenar muscle wasting

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6
Q

Which two tests can be used to test for carpal tunnel syndrome?

A

Phalen’s

Tinel’s

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7
Q

How can carpal tunnel syndrome be investigated?

A

Nerve conduction studies

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8
Q

How is carpal tunnel syndrome managed?

A

Splinting
Steroid injections
Surgical decompression

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9
Q

What is mononeuritis multiplex?

A

Damage to two or more peripheral nerves (which are usually not related)

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10
Q

What conditions are associated with mononeuritis multiplex?

A

Diabetes mellitus
SLE
Rh arthritis
Vasculitis

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11
Q

How is mononeuritis multiplex investigated?

A

Nerve conduction studies

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12
Q

Which axons are normally affected first by polyneuropathies?

A

Longer axons

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13
Q

What is the typical pattern of peripheral neuropathy?

A

Glove and stocking

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14
Q

How does peripheral neuropathy tend to start and then progress?

A

Starts peripherally and moves more proximally

Legs affected before arms

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15
Q

What is Guillain-Barre syndrome?

A

Rapidly progressive, ascending polyneuropathy

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16
Q

Which pathogens does Guillain-Barre usually follow?

A

Campylobacter
CMV
HIV
EBV

17
Q

Which component of the nervous system is attack in GB syndrome?

A

Myelin

18
Q

How long after infection does GB syndrome present?

A

2-4 weeks

19
Q

How does Guillain-Barre syndrome present?

A

Flaccid weakness in legs spreading to arms
Bilateral facial palsy
Dysphagia
Back pain

20
Q

How is Guillain-Barre syndrome investigated?

A

LP
Nerve conduction study
FBC for deficiency

21
Q

What is the management of Guillain-Barre?

A

IV IGs over 5 days
Analgesia
Early physio

22
Q

What does a patient with Guillain-Barre have to be monitored for?

A

Cardiac arrhythmia

Resp muscle weakness

23
Q

How long can recovery take in Guillain-Barre?

A

18 months