CNS infection Flashcards
What is the most common pathogen causing meningitis in <3m ?
Group B strep
E. coli
Listeria monocytogenes
What are the most common pathogens which cause meningitis?
Neiserria
S pneumo
H influenza
What are the most common pathogens cause meningitis in 18-50?
S pneumonia
Neiserries
What are the most common pathogens causing meningitis in >50?
S pneumo
L. monocytogenes
Gram neg bacilli
What are the most common pathogens causing meningitis in immunocompromise?
L monocytogenes
Gram neg bacilli
S pneumonia
H influenza
What pathogens cause meningitis following head trauma or procedure?
Staph
Strep pneumo
Pseudomonas
How does meningitis present?
Headache
Neck stiffness
Photophobia
Purpuric, non-blanching rash
What does LP show in bacterial meningitis?
High lactate Very high opening pressure Polymorphs (granulocytes) High protein Glucose <50%
What does LP show in viral meningitis?
Normal lactate Mild increase in opening pressure Monocytes (lymphocytes) Mild increase in protein >50% glucose
What does LP show in TB associated meningitis?
Very high lactate Very high opening pressure 10-100s mononuclear cells V high protein <50% glucose
What does LP show in autoimmune meningitis?
Mild increase in opening pressure
<100 WCC
Increased protein
>50% glucose
Meningitis in the elderly and neonates should be treated with which antibiotics?
Gentamicin and ampicillin
What in encephalitis?
Inflammation of the brain parenchyma
Which conditions are associated with autoimmune encephalitis?
SLE
Sarcoid
Anti-NMDA mediated encephalitis
Which viruses are associated with inflammation in brain parenchyma?
HSV1 HSV2 EBV VZV Mumps
