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RITE (Dr. Cheng, Berkowitz tables and path) > Neuropath: Neuro Devo and General Path > Flashcards

Neuropath: Neuro Devo and General Path Flashcards

1
Q

Three types of edema and pathophys

A

Vasogenic - Extracellular BBB
Cytotoxic- hypoxia - failure of NaK ATPase pump
Interstitial - hydrocephalus

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2
Q

Nissl stain

A

neuon cell bodies

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3
Q

H&E

A

general path exam

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4
Q

silver stain

A

axons and dendrites

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5
Q

Lipofuscin

A

accumulates with aging

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6
Q

Neuromelanin

A

accumulates neurons (SN and LC)

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7
Q

lethal neuronal injury

A

eosinophilic (red is dead) ferrugination.

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8
Q

Two viruses intranuclear inclusion bodies

A

HSV 1, CMV

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9
Q

Two viruses that can be intracytoplasmic and/or intranuclear

A

Measles (SSPE) and CMV

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10
Q

All inclusion bodies in degnerativ/metabolic diseases are

A

intracytoplasmia

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11
Q

Hamartoma definition

A

disorganized cells in the right location

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12
Q

Choristoma def

A

organized cells in the wrong location

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13
Q

Rosenthal fibers (eosinophilic masses) seen in three things

A

pilocytic astrocytoma, astrocytosis, Alexander’s disease

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14
Q

callosal agenesis, female, ocular abnormalties and infantile spasms

A

Aicardi’s

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15
Q

Chiari I not associated with _____

A

brain abnormalities

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16
Q

Chiari 1 herniation of tonsils and chiari II herniation of

A

tonsils / vermis

17
Q

Chiari III hindbrain herniates into

A

encephalocele

18
Q

chiari IV is cerebellar

A

hypoplasi

19
Q

Dandy-Walker malformation

A

posterior fossa continuous with fourth ventricle

20
Q

most common craniosynostosis

A

saggital

21
Q

Two most common craniofacial syndroms and main differences.

A

Crouzon’s #1 increased risk of hydrocephalus

Apert’s # 2 includes severe MRDD and GI/GU/Cardiac

22
Q

Chromsomal disorder with Alz, congenital heart disease and hypotelorism

A

trisomy 21

23
Q

Chromosomal disorder with hypertelorism (increased distance between eyes

A

5 p deletion Cri du chat

24
Q

Most frequent cause of hereditary MRDD

A

Fragile X

25
Q

cephalohematoma does not ____

A

cross suture lines

26
Q

kernicterus affects mainly the ____

A

globus pallidus

RITE (Dr. Cheng, Berkowitz tables and path) (17 decks)

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