Chapter 4 HA

Question 1

thunderclap headache/worse headache ever

Answer 1

SAH

Question 2

Indomethacin responsive HA

Answer 2

Hemicrania continua, paroxysmal

Question 3

HA red flags

Answer 3

Systemic symptoms,hx of cancer,immunodef, FNDs,new onset,thunderclap,age >50, precipitation by exertion/strain, positional changes, increased severity/frequency, seizure

Question 4

Sxs of GCA

Answer 4

HA with jaw claudication, scalp sensitivity, visual complaints, age >50, esr >50

Question 5

b/l trigeminal neuralgia differential

Answer 5

lyme, MS, sarcoid

Question 6

CADASIL

Answer 6

Notch 3, cerebral AD ateriopathy with subcortical infarcts and leukoencephalopathy

Question 7

Familial Hemiplegic Migraine (FHM) type 1

Answer 7

AD, chrom 19p13, CACNA1A, defective p/q calcium channel

Question 8

FHM type 2

Answer 8

AD, chrom 1q23, ATP1A2, defective a1a2 sodium-potassium atpase channel

Question 9

FHM type 3

Answer 9

AD, chrom 2q24, SCN1A, defective pre/post synaptic voltage gated sodium channels