Neurons & Synapses Flashcards

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1
Q

Neurons

A

cells specialized for conducting nerve impulses

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2
Q

Central Nervous System

A

nervous system that consists of brain and spinal cord

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3
Q

Peripheral Nervous System

A

nervous system that links CNS with receptors and effectors

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4
Q

Autonomic Nervous System

A

nervous system responsible for automatic processes, contains sympathetic and parasympathetic NS

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5
Q

Somatic Nervous System

A

nervous system that deals with sensory input and motor output

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6
Q

Neuron Cell Body

A

part of neuron that contains nucleus, ribosomes, and cytoplasm

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7
Q

Dendrites

A

part of neuron that receives messages

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8
Q

Axon Button

A

part of neuron that sends messages via neurotransmitter

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9
Q

Myelin Sheath

A

part of neuron that helps speeds up and boost action potential down the axon

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10
Q

Schwon Cell

A

cell type that makes up the myelin sheath

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11
Q

Sensory/afferent neuron

A

neuron that conducts nerve impulses from receptors to CNS

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12
Q

Interneuron/relay neurons

A

neurons that conduct nerve impulses within CNS (aka brain cells)

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13
Q

Motor/efferent neurons

A

neurons that conduct nerve impulses from CNS to effectors

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14
Q

Excitatory neurotransmitter

A

type of neurotransmitter that makes the cell more positive by letting in sodium to the cell and opening ligand-gated sodium channels, allowing for depolarization (ex. dopamine, noradrenaline)

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15
Q

Inhibitory neurotransmitter

A

type of neurotransmitter that makes the cell more negative by bringing potassium out of cell, creating hyperpolarization (ex. GABA)

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16
Q

Summation

A

where excitatory and inhibitory neurotransmitters compete to make the cell more positive and negative, it is the result of the total effect all neurotransmitters have on the voltage in the cell

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17
Q

Vitamin A

A

vitamin useful for eyes

18
Q

Vitamin B

A

vitamin useful for iron absorption

19
Q

Vitamin C

A

vitamin where deficiency causes scurvy

20
Q

Vitamin D

A

vitamin responsible for serotonin

21
Q

Vitamin K

A

vitamin responsible for blood clotting

22
Q

Folic Acid

A

vitamin useful for preventing spina bifida in childbirth

23
Q

Synapse/synaptic cleft

A

junction between the axon and the dendrite

24
Q

Reuptake

A

where excess neurotransmitter in the synapse is taken back up by the signaling cell, rather than docking to receptors in the receiving cell

25
Q

Process of Releasing a Neurotransmitter

A
  1. Action potential reaches terminal
  2. Ca2+ channels open
  3. Increased Ca2+ causes vesicles to release neurotransmitter
  4. Neurotransmitter crosses synapse through exocytosis
  5. Neurotransmitter either binds to receptors or excess is reuptaked, and ligand gated ion channels are opened
  6. Signal opens sodium or potassium channels in the cell and action potential may or may not occur, depending on the neurotransmitter
26
Q

Resting Potential

A

the charge difference across the neural membrane when a neuron is not firing (-70mV) and is maintained by the sodium potassium pump

27
Q

How many Na+ and K+ are pumped by ATPase?

A

3Na+ out of cell, 2K+ into cell

28
Q

Depolarization

A

the opening of sodium channels and the process of a neuron becoming more positive

29
Q

Action potential

A

charge difference when neuron is firing (30mV)

30
Q

Threshold Level

A

charge that must be reached inside of cell to trigger action potential (-55mV)

31
Q

Efflux

A

out of cell

32
Q

Influx

A

into cell

33
Q

Repolarization

A

the refractory period of a neuron’s firing, where the charge inside the neuron must move back to negative by opening the K+ channel

34
Q

Axon hillock

A

part of neuron where summation occurs, and all the electrical pulses from dendrites combine and potentially send an action potential

35
Q

Saltatory Conduction

A

describes the way that impulses jump from node to node down the axon, rather than moving continuously, as a result of the myelin sheath

36
Q

Nodes of Ranvier

A

part of the neuron that provides stopping points in the myelin sheath, gap in the myelin sheath needed for saltatory conduction

37
Q

Antiport mechanism

A

name of the mechanism of the ATPase ion pump, where Na+ and K+ are moved opposite ways through the cell membrane, instead of the same way

38
Q

Why is the refractory period important?

A

makes sure that signals only travel in one direction down the axon

39
Q

Batrachotoxin (BTX)

A

toxin produced by poison dart frog that covalently binds to Na+ ion channels, forcing them to stay open and preventing repolarization and relaxation of muscles (leads to paralysis)

40
Q

Curare

A

plant derivative that acts as a competitive inhibitor and inhibits nAChR (nicotinic actylcholine receptor) so it cannot fire (inhibits muscle contraction, so used as a muscle relaxant)

41
Q

Neonicotinoids

A

substance that leads to overstimulation of nAChR receptor because it covalently bonds to acetylcholinesterase (AChE), which is an enzyme used to get rid of excess acetylcholine, so it can no longer break down acetylcholine, used as a pesticide to create paralysis in bugs