Neuronal Differentation

Question 1

Neural

Answer 1

Neuron and Glia

Question 2

Neuronal

Answer 2

Neuron

Question 3

Steps of Neuronal devolopment

Answer 3

1. Generate Progeniter population (neuron than neuronal)
2. Devide progenoter populations (proliferation,self renewing)
3. Migrate to proper domain
4. Recieve cues from timing,enviorment,etc.
5. upregulate neuron specific regulatory pathways
6. produce branches to connect with other neurons
7. connect with other neurons/targets
8. cordiante with glia

Question 4

Floor plate/Roof plate

Answer 4

Floor-ventral

Roof - Dorsal

Made from shet folding up on itself - makes spinal cord with regions (floor and roof plates)

Question 5

Radial-Glia

Answer 5

radial migration of neurons out to edges of spinal cord

Question 6

Neuronal Branching

Answer 6

Many shapes/sizes

vast majority has three parts

• cell soma (transcription occours)
• dendrites
• single axon

Question 7

Neurites

Answer 7

unspecified branches extend from neuron (grow in differnt directions baised on enviorment)

one neurite defined as an axon - rest are either retracted or become dendrites

Question 8

Inital outgrowth

Answer 8

starts as Neurites

Question 9

axonal inital segment

Answer 9

protines localized in - determines that neuite becomes axion

(same thing as axion hillock)

though to be a filter area - prevent protines that arnt supost to be there

Question 10

cytoscelatal arangment

Answer 10

+in - Out - axion

both ways - dendrite

want protine to go out - want motor neuron to go - to +

Question 11

molecular charatristicis

Answer 11

neurotransmiters, synaptic vesicles, etc.

Question 12

axon on most neurons

Answer 12

only have one

Question 13

Growth cone

Answer 13

on axion - directs devolopment baised on extracellular cues