Cell Cell Communication Flashcards
Neuron
(Function, location, contact with, disorders)
sends and recieves neuronal info
CNS and PNS - everywhere
Oligrodrendrocites, microglia, astrosytes
MS Parkensisns, Alz.
Microglial
(Function, location, contact with, disorders)
resident immune cells of CNS
CNS
Oligrodrendocites, Astrocytes, BBB, neuronal
MS, menigits, autoimmune
BBB
Filter nutrients and other molecules
CNS
astrocytes, imune (microglia)
MS
Oligrodendrocites
mylen producing cell (schwan in PNS)
CNS
Neurons, microglia, astrocytes
MS, glioma (tumor)
Astrocytes
Form BBB, suport structure
CNS
interacts with all
Alz. ASD, Skitz.
MS Phenotypes
numbness, ingeling, vission problems, pain, waling dificulty
MS Disease is
demylenation of olegrodrensites
issue with electrical communication
Line of Stem cell to cell
Precusor (stem cell) can self renew
Progenetor can self renew
inmature differentated (unipotant) can self renew
mature differentated (unipotant)
levels of potantcy
totipotant - zygote only
pluripotant - can produce multiple diffrent cells
multi potant
unipotant - can only produce differentated cells
Basic communication stratiges
1) physical cell cell contact (tightly connectted) ex. gap junctions - cytoplasm communicates
2) cell surface Recptors and cell surface ligants - need to contact - driect - short range
3) cell surface receptors and secreted ligands- not direct - long range