neuromuscular junction Flashcards

1
Q

what is a refactory period

A

its a time during which an organ or cell is incapable of repeating a particular action

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2
Q

absolute refractory cooresponds refers to

A

depolarization and repolarization

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3
Q

relative refractory periods refer to

A

hyperpolarization

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4
Q

what is twitch

A

this is a single rapid contraction and relaxation of a muscle fiber or a group of muscle fibers due to a sigle action potential of the motor neuron

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5
Q

what happens in the latent period

A

this is the period btw when the stimulus is applied and when the first sign of the muscle contraction

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6
Q

at what period does the excitation - contraction coupling takes place

A

latent

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7
Q

what happens in the contraction period

A

this si the period btw the onset of the contractiona nd the endind of the contraction in which the peach tension occurs

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8
Q

what happens in the relaxation period

A

period btw the time of the peak tension to the point when tension returns to baseline

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9
Q

what are the other actions that takes place in the relaxation period

A

ca2 is being pumped back into the sacroplasmic reticulum
cross-bridge cycle stops
muscle is stretching back to its original length

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10
Q

does a muscle contraction curve have a refractory period

A

NO

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11
Q

what is excitation-contraction coupling

A

this is when an action potential causes depolarization in the myocyte membrane

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12
Q

a partial state of contraction of a skeletal muscle to maintain its optimal length during resting condition, even when a force isapplied to elongate the muscle is what

A

muscle tone

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13
Q

clinically muscle tone can be described as what

A

as the resistance, felt by the examiner during
passive stretching of a joint when the muscles are at rest

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14
Q

features of the muscle tone

A

Essential for maintaining body posture.
Reflect a state of preparedness to a movement
Prevents hypermobility of joints
Declines during REM.

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15
Q

types of hypertonia

A

spasticity
rigidity
spasm

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16
Q

classification of muscle tone

A

postural and phasic

17
Q

truths about postural muscle tone

A

seen in axial muscles
gravity is an important factor
results from a steady stretch on the muscles
manifests as prolonged muscle contraction

18
Q

truths about the phasic tone

A

assesed clinically as a rapid and short duration
results from a rapd stretch of tendon

19
Q

muscle tone is regulated by what

A

spinal mechansim and supraspinal mechanisim

20
Q

spinal mechanism is dependent on the interaction betw what

A

muscle spindle
spinal cord
interneurons

21
Q

supraspinal is regulated by

A

facilatatory and inhibitory long tracts and cerebelum

22
Q

sudden rapid stretch of a muscle stimulates what

A

nuclear bag fibers and 1a afferents

23
Q

rapid stretch is the clinical bases of what

A

deep tendon reflex

24
Q

sustained stretch stimulates what

A

nuclear chaon fibers and type 2 a

25
Q

static stretch response is the physiological basis of what

A

maintainng muscle tone

26
Q

supraspinal control consist of

A

supraspinal control through descendong long tracts
and cerebellum

27
Q

role of cerebellum

A

medaila part of the anterior lobe activates medullary reticular formation and inhibits muscle tone

lateral part activates pontine reticular formation and facilitates muscle tone indirectly

cerebellar lesions produce hypotonia

28
Q

hypertonic constsit of what

A

spasticity
dystonia and rigidity

29
Q

the involuntary muscle hyperactivity consists of what

A

spasticity sensus strictu
rigidity
dystonia
spasms

30
Q

postive consequences of spasticity

A

helps in standing and walking
reduces edema
delays muscle atrophy
prevent osteoporosis
aids in breathing

31
Q

A muscle with a shorter length and reduced cross-section produces what

A

less force