multiple sclerosis Flashcards

1
Q

myelin sheath diseases of the cns can be divided into

A

dysmyelinating and deymyelinating

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2
Q

functions of the myelin

A

an insulator
speeds up rate of impulses
protectsthe axon from damage
repairs injured fibers

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3
Q

ms is what typye of deymyelinating disorder

A

inflammatory immune disorder

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4
Q

types of demyelinating disorders

A

inflammatory
infectous
granulomatous
myelin disorders
toxic

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5
Q

what is multiple sclerosis or ms

A

is a chronic, inflammatory , progressive demyelinating and neurodegenerative dieseas that involves immune mediated attacks on the cns

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6
Q

what can be seen in ms or characteristics

A

relapses and remisions
inflammation and damage to the myelin sheath
diagnosed btw 20-30
females are more likely

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7
Q

sites where the myelin is lost appeared as hard areas is called what

A

plaques or lesions

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8
Q

what are the risk factors that affect ms

A

environmental factors
genetic
familial

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9
Q

some symptoms of ms

A

numbness
pain
fatigue
muscle spasm
walking difficulty

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10
Q

less common symptoms of ms

A

speech prob
swallowing
seizure
loss of taste
tremor
breathing problems
hearing loss

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11
Q

what is the most common motor problems in the ms

A

upper extremities are hypotonic
lower extremities are spastic

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12
Q

what are the signs we can see in the senory issue

A

parasthesis
dysethesias
Lhermittes sighn
pain
trigeminal
proprioception deficits

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13
Q

signs seen when the brainstem is affected

A

dysarthria
dysphagia

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14
Q

inflammation of the cns causes what

A

excacerbation of ms

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15
Q

diagnosis of ms

A

ct mri
lumbar puncture
physical exam
evoked potential test

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16
Q

types of ms

A

CIS Clinically Isolated
Syndrome

RRMS RelapsingremittigMS

SPMS Secondary progressive MS

PPMSPrimary progressive ms

17
Q

explain cis breifly

A

the episode must last for 24 hours and it has the characteristics for multiple sclerosis but doesnt meet the criteria for a diagnosis

18
Q

what happens in rrms

A

most common
characterized by attacks in which these attacks may include partial or full remissions or recovery

19
Q

what happens in spms

A

it starts with a relapsing perios and just gets worse overtime or progressive worsening and patients with rrms may progress to spms

20
Q

what hapens in ppms

A

worsening neurologic functions from the onset without any relapses or remissions

21
Q

factors that incrase the ms

A

trauma
pregnancy
extreme fatigue
hot bath
hot weather

22
Q

factors used for assessment

A

type of ms
drug used
last attack time

23
Q

explain the following points in the edss scale for ms
1.5,6.0,7.0

A

1.5 no disabillity
6.0=needs assistance to walk like a crutch or crane
7.0=starts to use wheelchai cause the patient cant walk

24
Q

in the management of ms what are the treatments of the following
symptoms
relapses
disease modifying therapies

A

symptms=managed with medications
relapses=treated with high dose glucocoricoids
disaese modifying therapies=reduce the frequency of relapses