Neurology and The Brain Flashcards
What are the three primary brain vesicles?
Forebrain (prosencehalon)
Midbrain (mesencephalon)
Hindbrain (rhombencephalon)
What forms from each vesicle of the brain?
Prosencephalon
- Telencephalon
- Diencephalon
Mesencephalon
Rhombencephalon
- Metencephalon
- Myelencephalon
What forms from the diencephalon?
thalamus, hypothalamus, pineal gland, pituitary gland
What forms from the telencephalon?
cerebral hemispheres, hippocampus, basal ganglia
What forms from the mesencephalon?
superior and inferior colliculi
What forms from the metencephalon?
cerebellum, pons
What forms from the myelencephalon?
medulla
What does the choroid plexus do?
Produces CSF
What are the ventricles of the brain?
Lateral ventricles
III ventricle
IV ventricle
Cerebral aqueduct connecting III and IV ventricles
Describe the blood supply to the brain
The two ICAs enter skull through carotid canal to supply the brain
Two vertebral arteries (branches of subclavian) also enter skull through foramen magnum to supply brain
Branches of the ICA join those of opposite side and with PCA (branch of basilar artery) to form a continuous circle at the base of the brain
What branches of the ICA supply the brain?
Anterior cerebral
Middle cerebral
Posterior communicating
What does the vertebro-basilar system comprise of and what does it supply?
The two vertebral arteries join together to form a basilar artery on the ventral surface of the brainstem.
This vertebro-basilar system gives branches that supply the brainstem and cerebellum.
*At level of midbrain basilar artery divides into the two posterior cerebral arteries
Describe the vascular areas of the brain (i.e. the cerebral artery supply)
Anterior cerebral; medial aspect of cerebral hemispheres excluding occipital lobe
Middle cerebral; lateral aspect of cerebral hemispheres
Posterior cerebral - inferior aspect of cerebral hemispheres and occipital lobe
Describe venous drainage of the brain
Superficial and deep veins drain into venous sinuses which lie between 2 layers of dura mater
Dural venous sinuses join and ultimately drain into internal jugular veins
Describe the medulla (oblongata)
Cavity is IV ventricle
Continues as spinal cord at level of foramen magnum
Surface features;
- pyramids and their decussation
- Olives laterally
- Connected to cerebellum by inferior cerebellar peduncle
- Cranial nerves IX, X, XI and XII exit from its surface
What is present in the white matter of the medulla?
- pyramidal tract
- medial lemniscus
- inferior cerebellar peduncle
- other tracts
What is present in the grey matter of the medulla?
- cranial n nuclei and inferior olivary nucleus
- nuclei of reticular formation (vital centres)
- sensory nuclei (gracile and cuneate)
Describe the pons
IV ventricle is posterior to it
Surface features;
- middle cerebellar peduncle
- cranial nerves V, VI, VII and VIII originate from its surface
What is present in white matter of the pons?
- Middle cerebellar peduncle (centripetal fibres)
- medial lemniscus (sensory)
- pyramidal tract (motor)
What is present in the grey matter of the pons?
- cranial n nuclei
- pontine nuclei
- nuclei of reticular formation
Describe the midbrain
Develops from mesencephalon
Central cavity = cerebral aqueduct
Surface features;
- cerebral peduncle
- superior cerebellar peduncle
- superior and inferior colliculi
- Origin of cranial n III and IV
What is present in a midbrain section?
Central cavity - cerebral aqueduct
Periaqueductal grey matter with nucleus for III and IV Cranial nerves
White matetr with embedded nuclei (red nuclei)
Substantia nigra (functionally part of basal ganglia)
Describe the cerebellum
Right and left hemispheres separated by vermis
Each hemisphere has anterior, posterior and flocculondular lobe
Surface has sulci and folia
Three cerebellar peduncles connect it to brainstem
Brodmann Areas 44, 45
Broca’s area
- frontal lobe of dominant hemisphere
- speech production
Brodmann Areas 3, 1, 2
Primary sensory area
Brodmann Area 4
Primary motor area
Brodmann Area 17
Primary visual cortex
Brodmann Area 22
Primary auditory cortex
Brodmann Areas 39, 40
Wernicke’s area
- temporal lobe left side
- speech comprehension
Which cranial nerves emerge from the pontomedullary junction?
VI, VII, VIII
What is the function of the medullary pyramids?
carry motor fibres to spinal cord and brainstem
What is the middle cerebellar peduncle made up of?
Centripetal fibres
what is the midline structure connecting the two cerebellar hemispheres?
vermis
What parts of cerebellum sit atop foramen magnum?
Cerebellar tonsils
What is the name of the fissure separating the cerebral hemispheres?
Longitudinal fissure
What type of nerve fibres are carried in corpus callosum?
Commissural fibres
What parts of vertebrae are removed to open up spinal cord?
lamina - laminectomy
What structures might you encounter during a laminectomy?
Lamina
Spinor erectae muscles
Denticulate ligament
What vertebral level does spinal cord terminate?
Adult; L1/L2
Child; L3/L4
At what vertebral level do the dura and arachnoid matter terminate?
S2
What happens to the pia mater inferior to the spinal cord?
becomes filum terminale
At what vertebral level do the internal carotids arise?
C4
How does the basilar artery form and to which brainstem part is it most closely related?
2 vertebral arteries join at base of skull
Pons
What links the internal carotids to the PCAs?
Posterior communicating artery
Which artery connects the ACAs?
Anterior communicating artery