Neurology Flashcards

1
Q

Most common cause of status epilepticus

A

stroke

*acute reasons more likely

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2
Q

What is stat epilepticus

A

sz over 5 minutes practically (but also sorta 30 minutes)

causes permanent damage

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3
Q

Antibiotics that cause sz

A

aminoglycosides and fluoroquinolones

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4
Q

Non-Epileptic but Organic Seizure

A

Metabolic
Drugs
EtOH withdrawal
Febrile seizure

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5
Q

How do you treat status epilepticus

A

IM Midazolam 10 mg

IV lorazepam 4 mg (aka ativan)
IV diazepam 10 mg

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6
Q

If benzos fail at stopping status epilepticus, what med now?

A

Fosphenytoin 20 mg/ kilo

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7
Q

what two ways do pretty much all antiepileptics work by

A

Na channel block

modulate GABA

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8
Q

Lamotrigine titrated for ___ time b/c of ______

A

6 week titration

most likely to cause steven johnson/ten

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9
Q

What two drugs treat only focal sz

A

lacosimide- na block (SI*, arrhythmia)

Gabapentin- Ca block (Sedation*, ataxia)

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10
Q

Who do you screen/ how to screen to be on carbamazepine

A

asians with HLA screening to avoid skin rxns

1st line for trigeminal neuralgia

s/e: hyponatremia (realistically) moa is na block

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11
Q

Lamotrigine use

A

bi polar or sz drugs
na block

BEST IN CHILDBEARING WOMEN!!!

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12
Q

Sz drugs that are also mood stabilizer

A

valproate
gabapentin
lamotrigine

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13
Q

what sz drug is:

BEST IN CHILDBEARING WOMEN!!!

A

Lamotrigine

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14
Q

what sz drug is most teratogenic

A

valproic acid- neural tube defects

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15
Q

what is primidone

A

breaks down into phenobarbital

rx for essential tremor

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16
Q

what sz drug is the most cognitive dulling

A

topomax (aka dopamax)

17
Q

valporic acid side effects

A

neural tube defects, fat, bald, and shaky

18
Q

what is the worse meningitis

A

bacterial

ceftriaxone and acyclovir prophylaxis

19
Q

what exactly does phenytoin and carbazapine do to babies

A

Fetal hydanation syndrome

mid face hypoplasia
microcephaly 
cleft lip
digital hypoplasia
hirsutism 
development delay