Neurology Flashcards

1
Q

Intervention in TBI that has been shown to improve outcomes more than any other

A

Preventing hypotension

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2
Q

Lorazepam dose of status epilepticus

A

0.1 mg/kg

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3
Q

Findings in cushings reflex

A

Bradycardia
Widened pulse pressure
irregular breathing

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4
Q

Spinal cord syndrome where there is total loss of vibration, proprioception, pain and temperature, and motor loss bilaterally below the level of the lesion

A

Transverse cord syndrome

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5
Q

Spinal cord syndrome where there is loss of motor and proprioception below the ipsilateral side of the lesion and loss of pain and temperature below the contralateral side

A

Hemicord lesion aka Brown-Sequard

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6
Q

Spinal cord syndrome where there is upper extremity motor and sensory loss in a cape like distribution

A

Central cord lesion

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7
Q

Spinal cord syndrome where there is loss of vibration and position below the level of the lesion bilaterally

A

Posterior cord syndrome

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8
Q

Spinal cord syndrome where there is loss of motor function and pain/temperature below the level of the lesion bilaterally

A

Anterior cord syndrome

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9
Q

Condition where there is autoimmune demyelination of the white mater following an infection

A

Acute Disseminated Encephalomyelitis (ADEM)

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10
Q

First line treatment for ADEM

A

solumedrol

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11
Q

Second line treatment for ADEM

A

Plasmapheresis

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12
Q

Most sensitive test for spinal abscess

A

MRI

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13
Q

Condition post stroke where there is a large ischemic area and risk of herniation

A

Malignant middle cerebral artery syndrome

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14
Q

Only treatment for malignant middle cerebral artery syndrome that has been shown to reduce mortality

A

Hemicraniectomy

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15
Q

Test to check for cerebral vasospasm

A

transcranial doppler

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16
Q

Test to look for large vessel occlusion in stroke

A

CT or MR angio with perfusion or diffusion imaging

17
Q

ICP value above which there are worse outcomes

A

> 20

18
Q

CPP associated with worse outcomes

A

> 70

19
Q

In elevated CPP what are the 2 treatment options

A

Lower MAP or raise ICP so long as the ICP does not cross > 20

20
Q

Variant of GBS that has early cranial nerve dysfunction and respiratory failure

A

Miller fisher

21
Q

Treatment for GBS

A

IVIG and/or plasmapheresis

22
Q

Treatment for dysautonomic shock in GBS

A

Midodrine and fludrocortisone

23
Q

Antiepileptic given for 7 days in TBI to prevent seizures

A

Phenytoin

24
Q

Name of the protein responsible for parkinsons and lewy body dementia

A

Alpha-synuclein

25
Q

Treatment that improves mortality in intraventricular hemorrhage

A

Intrathecal TPA until 85% of the blood has been reduced

26
Q

Is there a difference between open and closed external ventricular drain in terms of mortality benefit?

A

No

27
Q

What direction do eyes move in acute stroke

A

Toward the lesion and away from the hemiparesis

28
Q

What direction do eyes move in seizures

A

Away from the lesion and toward the hemiparesis

29
Q

2 causes of lymphocyte predominant CSF in meningitis

A

Listeria and TB

30
Q

Can dialysis remove bone marrow particles in fat embolism?

A

No (no treatment works)

31
Q

Memory loss and new intracerebral hemorrhage from microhemorrhages suggests what diagnosis

A

Cerebral amyloid angiopathy

32
Q

Can anything prevent future strokes in cerebral amyloid angiopathy?

A

No

33
Q

Platelet transfusion threshold in patient’s with intercerebral hemorrhage despite being on antiplatelet therapy

A

< 50k

34
Q

What are the two mechanisms of vasoconstriction in patient’s who are at risk of herniation

A

Therapeutic hyperventilation and systemic cooling

35
Q

To what level do you cool a patient to prevent herniation?

A

33C

36
Q

To what level do you aim for CO2 in therapeutic hyperventilation to prevent brain herniation?

A

20

37
Q

What autoimmune paraneoplastic syndrome is commonly associated with ovarian or testicular teratomas

A

anti-NMDA receptor encephalitis syndrome

38
Q

What is the targeted temperature in TTM?

A

< 38C