Neurology

Question 1

ptosis, fatiguability, anti-Ach receptor antibodies, thymoma

Answer 1

myasthenia gravis

Question 2

AntiJo1, heliotropic rash, gottrons papules, elevated CK, weakness

Answer 2

dermatomyositis

Question 3

weakness, associated with scleroderma, sjogrens and lupus, ILD, CD8 elevation in muscle biopsy. Treated with steroids and IVIG

Answer 3

polymyositis.

Question 4

wrist drop due to weakness, minimal sensory loss to dorsal hand and wrist. Due to compression along the spiral groove of the humerus

Answer 4

radial nerve palsy

Question 5

prayer and tinel sign

Answer 5

carpal tunnel.

Question 6

acute demyelinating polyneuroapthy, associated post-infection, respiratory failure, bulbar weakness, areflexia, proximal pain, treatment is IVIG

Answer 6

guillan barre syndrome

Question 7

subacute onset of malfunction in multiple peripheral nerves due to damage to vessels supplying the peripheral nerces. associated with ct diseases like polyarteritis nodosa, eGPA, GPA, cryoglobulinemia, SLE, sjogrens etc. Symptoms are patchy/assymtetric, distal> proximal pain.

Answer 7

mononeuritis mulitplex

Question 8

duplication of PMP22 gene, distal weakness, chapagne bottle lefs, interosseous wasting, hammertoes

Answer 8

charcot marie tooth, a fereditary demyelinating neuropathy.

Question 9

autosomal dominant CAG repeats with chorea, leading to ballism.

Answer 9

huntingtons chorea

Question 10

alpha-synuclein accumulats in the lewy bodies–> neurotoxicity of substania nigra –> loss of DA neurons. leads to brady kineseia, rigidity, tremor, or postural instability. Also associated with neuropsychiatric symptoms including weird dreams, dementia (lewy body demensia)

Answer 10

parkinsons

Question 11

54321 SULTANs for migraines

Answer 11

5 symptoms
lasting 4 hours to 3 days
2 of unilateral, throbbing, moderate-severe, worse with activity
1 of photophobia, phonophobia,aura nausea