Neurologie Flashcards

1
Q

Anticorpi specifici sindromanelor paraneoplazice neurologice:

A

Ac. anti-Hu
Ac. anti-Yo
Ac. anti-Ma2/Ma1
Ac. anti-CV2
Ac. anti-Ri
Ac. anti-Tr
Ac. anti-amfilizina

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2
Q

Sindroame paraneoplazice neurologice (cadran 26.27):

A

ataxie cerebeloasa
encefalita limbica
opsoclonus-mioclonus
encefalomielita progresiva cu rigiditate si mioclonus (PERM)

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3
Q

Anticorpii anti-NMDA apar in:

A

Encefalita limbica asociata unui teratom

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4
Q

Anticorpi intalniti in encefalita limbica non-paraneoplazica:

A

Ac. anti - canale de K voltaj dependente (VGKC)
Ac. anti-glycine receptor (anti-GlyR Ab asociati cu PERM)

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5
Q

Miastenia Gravis este asociata cu urmatorii anticorpi:

A

Ac. anti-receptor de acetilcolina
Ac. anti-MuSK (Muscle Specific Kinase)

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6
Q

Anticorpii anti-canale de Calciu voltaj dependente (VGCC) sunt asociati cu:

A

Sindrom miastenic Lambert-Eaton

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7
Q

Ce anticorpi se pot intalni in neuromielita optica?

A

Ac. anti-aquaporina 4 (AQP4-Ab sau NMO-IgG)

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8
Q

Sindromul “omului rigid” (stiff person syndrome) se asociaza cu urmatorii anticorpi:

A

Ac. anti-GAD (de asemenea intalniti in DZ tip 1)

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9
Q

Urmatorul anticorp se asociaza cu mielita transversa:

A

Ac. anti-MOG (myelin oligodendrocyte glycoprotein)

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10
Q

Anticorpi intalniti in neuropatii periferice :

A

Ac. anti-gangliozide
Ac. anti-MAG (myelin associated glycoprotein)

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11
Q

Encefalita Hashimoto se asociaza cu urmatorul anticorp:

A

ac. anti-TPO

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12
Q

Dermatomiozita / Polimiozita se asociaza cu urmatorii anticorpi:

A

ac. anti-Jo1
ac. anti - ARNt sintetaza
ac. anti - SRP (signal-recognition particle)

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13
Q

Coma are un scor GCS…

A

≤ 8

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14
Q

Delirul este o stare de confuzie in care principala trasatura este…

A

lipsa atentiei + tulburari de comportament, cognitie, orientare si fluctuatii ale nivelului de constienta (agitatie psihomotori –> hipoactivitate)

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15
Q

Care sunt cele 4 mecanisme implicate in alterarea starii de constienta

A

Leziuni ale trunchiului cerebral
Compresiunea trunchiului cerebral
Leziuni cerebrale difuze
Leziuni difuze corticale

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16
Q

Leziunile cu efect de masa din fosa posterioara pot cauza:

A

compresiunea trunchiului cerebral si hidrocefalie

17
Q

Leziunile cerebrale difuze pot aparea in:

A

tulburari de metabolism sau anumite toxice (alcool, sedative, uremie, hipercapnie)

18
Q

Leziunile difuze corticale care pot produce coma:

A

meningita
leziuni hipoxic-ischemice cauzate de un stop cardiac

19
Q

Cele mai comune cauze de coma (procente):

A

tulburari metabolice 35%
droguri si toxice 25%
leziuni cu efect de masa 20%
altele: trauma, AVC sau infectii SNC

20
Q
A