Neurological and Endocrine Disorders Flashcards
Neurological & Endocrine Disorders
A type of ischemic stroke that occurs when a blood clot forms in an artery that supplies blood to the brain
thrombotic stroke
Neurological & Endocrine Disorders
Idris is in a serious car accident that causes a traumatic brain injury. After regaining consciousness in the hospital, Idris has anterograde amnesia and retrograde amnesia that affects memories for the ten months prior to the accident. When Idris’s long-term memories begin to return, he’s most likely to recall which types of memories first?
longer-term memories
Neurological & Endocrine Disorders
Migraine headaches have been linked to abnormal levels of:
serotonin
Neurological & Endocrine Disorders
Which is not a characteristic of hypothyroidism?
a) decreased libido
b) heat intolerance
c) confusion
d) unexplained weight gain
b) heat intolerance
Neurological & Endocrine Disorders
A client with __________ tells her therapist that, since her traumatic brain injury, she has had trouble disciplining her children because, when she tells them she’s angry about what they’ve done, she doesn’t sound angry and, as a result, they don’t listen to her. As the client describes the problems she has with her children, she speaks in a monotone.
aprosodia
Neurological & Endocrine Disorders
an MRI-based technique that is used to detect abnormalities in the brain’s white matter by measuring the spreading of water molecules in the tissues
diffusion tensor imaging
Neurological & Endocrine Disorders
a type of seizure that causes a very brief loss of consciousness, often without being noticed, typically lasting 10-20 seocnds and characterized by a blank stare
generalized onset non-motor
Neurological & Endocrine Disorders
levodopa is most effective for which symptom(s) of Parkinson’s?
bradykinesia
Neurological & Endocrine Disorders
Parkinson’s disease has been linked to a degeneration of dopamine-producing cells in which area of the brain
substantia nigra
Neurological & Endocrine Disorders
medical term for a stroke that is caused by an interruption of blood flow to the brain that causes brain cells to die / a loss in neurological functioning.
cerebrovascular accident (CVA)
Neurological & Endocrine Disorders
all of the following are risk factors for stroke except (and which is the largest risk factor?)
a) obesity
b) agranulocytosis
c) hypertension
d) male gender
e) AA race
b) agranulocytosis
c) hypertension
other risk factors: heart disease, diabetes, cigarette smoking, older age, family hx of stroke, heavy alcohol consumption
Neurological & Endocrine Disorders
what are the 2 main types of stroke and what causes each of them
1) ischemic stroke: caused by a blood clot blocking blood flow
2) hemorrhagic stroke: caused by bleeding in the brain (these are further categorized by where the bleeding occurs)
Neurological & Endocrine Disorders
this is most common type of stroke, which is caused by a blood clot blocking an atery in the brain
ischemic
Neurological & Endocrine Disorders
this is a less common type of stroke caused by bleeding in the brain
hemorrhagic
Neurological & Endocrine Disorders
this type of stroke is caused by a blood clot in a cerebral artery that supplies blood to the brain
thrombotic stroke
Neurological & Endocrine Disorders
this type of stroke is caused by blockage in a cerebral artery due to a blood clot developing in the heart or elsewhere in the body and then traveling through the bloodstream to the brain
embolic stroke
Neurological & Endocrine Disorders
this type of stroke is also known as a “mini-stroke,” is caused by temporary blockage of bloodflow to the brain, and is usually a warning sign that a more severe stoke may occur in the future
transient ischemic stroke (TIA)
Neurological & Endocrine Disorders
this type of stroke is due to bleeding in the brain and occurs when there is a rupture in a cerebral artery within the brain or in the space between the brain and the membrane that covers the brain
hemorrhagic stroke
Neurological & Endocrine Disorders
this type of hemorrhage occurs a cerebral artery ruptures in the brain and bleeds into the brain tissue
intracerebral hemorrage
Neurological & Endocrine Disorders
this type of hemorrhage occurs in the space between the brain and the membrane that covers the brain
subarachnoid hemorrhage
Neurological & Endocrine Disorders
symptoms of a stroke depend on which ____ is involved.
artery
Neurological & Endocrine Disorders
this artery is the largest branch of the internal carotid artery, supplies a large area of the brain, and is the most commonly affected artery in a stroke
middle cerebral artery
Neurological & Endocrine Disorders
a stroke involving the middle cerebral artery would damage what area of the brain & result in these symptoms
- frontal, parietal, & temporal lobes
-
symptoms
aphasia (speech difficulties; due to damage in the dominant hemisphere)
contralateral neglect (neglecting one side of visual field; non-dominant hemisphere affected)
other sxs: facial weakness, arm paralysis, & sensory loss
Neurological & Endocrine Disorders
a stroke involving the posterior cerebral artery would result in these symptoms…
- headache
- nausea & vomiting
- memory loss
- speech difficulties (Dysarthria)
- ataxia
Neurological & Endocrine Disorders
A stroke involving the anterior cerebral artery would result in these symptoms…
- executive dysfunction (e.g., impaired insight & judgment)
- mutism
- urinary incontinence
- confusion
Neurological & Endocrine Disorders
these types of TBIs depend on the injury’s location and severity, while these types of TBIs usually cause more widespread damage
open; closed
Neurological & Endocrine Disorders
this type of head injury may produce a loss of consciousness; and, when individuals regain consciousness, they usually experience a variety of mental (e.g., emotional, cognitive, & behavioral) & physical symptoms
TBI
Neurological & Endocrine Disorders
cognitive symptoms of a TBI may include what symptoms associated with memory problems
anterograde & retrograde amnesia
Neurological & Endocrine Disorders
the duration of cognitive symptoms after TBI is a good predictor of what
recovery
Neurological & Endocrine Disorders
when retrograde amnesia occurs after a TBI, which memories are affected more? when lost memories begin to return, those from the most ____ past are recovered first
recent long-term; distant
Neurological & Endocrine Disorders
physical symptoms of a TBI include all of the following except:
a) nausea and vomiting
b) headaches
c) strokes
d) seizures
c) strokes
physical sxs also include: fatigue, loss of consciousness, pupil dilation, weakness or numbness in limbs, & difficulty w/ balance & coordination
Neurological & Endocrine Disorders
which of the following is the term for a neurological condition that affects the ability to express or understand prosody (i.e., variations in the rhythm, pitch, timing, & loudness of speech that are used to convey emotional info)
a) ataxia
b) aprosodia
c) anasognosia
d) asomatognosia
b) aprosodia (the inability to produce or comprehend affective components of language)
Neurological & Endocrine Disorders
post-traumatic seizues can occur within what timeframe following a TBI and can often be successfully treated with anti-seizure meds
1 week
Neurological & Endocrine Disorders
this symptom of a TBI can occur more than 1 week after and is typically harder to treat
post-traumatic epilepsy (PTE)
Neurological & Endocrine Disorders
the following are alternative treatments used when medication is ineffective to treat this neurological disorder
a) vagus nerve stimulation
b) responsiveness neurostimulation (RNS)
c) surgery
post-traumatic epilepsy (PTE)
Neurological & Endocrine Disorders
some evidence suggests that seizures following TBI are linked to atrophy in what brain areas
temporal lobe & hippocampus
Neurological & Endocrine Disorders
describe the typical prognosis for a TBI
at 3 months, 1 year, lifetime
- most recover within first 3 months with substantial improvement during the 1st year
- many people continue to have symptoms indefinitely, especially with moderate to severe injury
Neurological & Endocrine Disorders
this disease is an incurable neurodegenerative disorder that is mostly inherited and involves a general lack of coordination & an unsteady gait
Huntington’s
Neurological & Endocrine Disorders
this autosomal dominant gene on chromosome 4 is responsible for Huntington’s disease
huntington (HTT) gene
Neurological & Endocrine Disorders
Offspring of a 1 person with the huntington (HTT) gene have a ____% chance of inheriting Huntington’s, while offspring of 2 people with this gene have a ____% change of inheriting Huntington’s
50%; 75%
Neurological & Endocrine Disorders
Huntington’s is primarily associated with neurodegeneration in these brain areas
basal ganglia (specifically the striatum)
Neurological & Endocrine Disorders
neuroimaging studies of Huntington’s have found that atrophy in these 2 brain areas is apparent years before the onset of symptoms
caudate nucleus & putamen
Neurological & Endocrine Disorders
Huntington’s is associated with abnormal levels of this neurotransmitter
dopamine
also, GABA & glutamate
Neurological & Endocrine Disorders
symptoms of Huntington’s most often appear between these ages and life expectancy is usually this many years after onset of symptoms
- 30 to 50 years
- 10 to 30 years
Neurological & Endocrine Disorders
progression of Huntington’s disease varies, but typically these symptoms precede cognitive & motor symptoms. List these symptoms.
affective
* emotional changes: irritability, depression, aggression
Neurological & Endocrine Disorders
typical progression of symptoms with Huntington’s suggests that these symptoms are not just a reaction to the distress but instead a manifestation of what
underlying pathological changes
Neurological & Endocrine Disorders
what primary motor symptom is associated with onset of Huntington’s? Symptoms associated with later stages and criteria for mild or major neurocognitive disorder?
three C’s
Chorea (involuntary, jerky movements)
other symptoms:
Cognitive decline (memory problems, difficulty concentrating)
Changes in mood/behavior (irritability, depression, aggression)
Neurological & Endocrine Disorders
treatment goals for Huntington’s
- no cure
- relieve symptoms & improve quality of life
Neurological & Endocrine Disorders
this disease is an incurable neurodegenerative disorder that produces prominent motor symptoms and is the result of a combination of genetic & environmental factors
Parkinson’s
Neurological & Endocrine Disorders
neurotransmitters & low/high levels of each associated with Parkinson’s
D.A.N.G.
low levels
* dopamine
* acetylcholine
* norepinephrine deficiency
high levels
* glutamate