neuroimaging Flashcards

1
Q

MRI

A

scan and create images of brain structure

beneficial to detect brain abnormalities
test structural differences in brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how does an MRI work

A

large magnets

take slices to construct a 3D model
- coronal plane
- horizontal plane
- sagittal place

lots of images taken in rapid succession whilst people do things
enables us to look at brain function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

how does an fMRI work?

A

determines activity by detecting changes in the magnetic response of haemoglobin

iron molecule found in haemoglobin gives blood magnetic properties

when magnet presented to brain, haemoglobin molecules line up

haemoglobin lose oxygen in areas of high brain activity
makes haemoglobin more magnetic and therefore molecules respond stronger to magnetic field

measured changes are BOLD
blood oxygen level dependant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

the haemodynamic response function

A

cant measure neuron spiking
only measure th energy craving after the activity
indirect measure of neuron activity
measures metabolic consequences 4-6 seconds after

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

PET scan

A

uses same machine as an fMRI

radioactive crater substance injection to make blood flow more visible

more direct measure of blood flow compared to magnetic field differences

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

subtraction method

A

used to see specific brain functions
keep entire environment the same except what is being observed
can be compared to show difference

measure 2 variations of same mental function
only differ in one aspect
observed difference must be due to variation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PET vs fMRI

A

PET has better:
signal to noise ratio
higher sensitivity to blood flow
movement less problematic

fMRI better:
resolution
clearer image
more accurate - better to detect locations
quicker than PET
but prone to movement artifacts (noise)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

diffusion tensor imaging DTI

A

makes nerve fibre tracts (physical connections between neuron tracts) visible
can be used to build realistic models of neural structures

explains how far away areas of the brain can work together to complete a function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

central principle of cognition

A

most of our experience is multidimensional
specific functions are both localised and distributed across different areas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

functional connectivity

A

when neurons work in synchronisation during certain tasks
neurons do not need to be physically connected to work together and form neural networks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

empirical methods

A

used to experimental confirmation, exploration and debunking

behaviour
self report
- questionnaires and interviews

observable
- reaction times an pupil dilations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly