Neurohistology Flashcards
Three types of cells found in the nervous system
1) Neurons
2) Gila cells
3) Specialized Cell Types
Immunofluorescence
Method that relies on the use of antibodies chemically labeled with fluorescent dyes to visualize molecules under a light microscope.
What is immunofluorescence commonly used for?
used to stain microbiological cells
What is immunohistochemistry used for?
used to stain sections of biological tissue
Advantage of Long Dendrite
Receive more input from other neurons
Dendrites
Short-branched fibers that convert chemical information from other neurons or receptor cells into electrical signals
Axons
An elongated fiber that transmits electrical signals to terminal regions (away from cell body) for communication with other neurons or effectors
Cell Body (Soma)
Contains the nucleus and organelles, where essential metabolic processes occur to maintain cell survival
Where are interneurons found?
Lie between sensory and motor neurons
- found only in CNS
Interneuron Function
They receive information from other neurons (either sensory neurons or interneurons) and transmit information to other neurons (either motor neurons or interneurons).
Where is genetic info stored in the cell?
Mitochondria and Nucleus
Six Types of Neurons
1) Cortical pyramidal cell
2) Retinal Bipolar Cell
3) Retinal Ganglion Cell (branches out)
4) Retinal amacrine cell (interneuron, no axon)
5) Neurons in mesencephalic nucleus of cranial nerves V (no axon)
6) Cerebellar Purkinje Cells (huge amount of dendrities)
Indirect Immunohistochemistry
Uses an unlabeled primary antibody to detect the antigen of interest in the tissue. A secondary labelled antibody is then used to bind to the primary antibody.
