Neurogenomics Flashcards
What is neurogenomics?
Linking genetic variability to social behaviours, and vice versa
What is epigenetic variation?
Differences in gene expression that are NOT due to genotype
What are the sources of genetic complexity?
> Alternative splicing isoforms
> Expressed non-coding RNAs
What are the genetic sources of variation?
> Single Nucleotide Polymorphism
>Copy Number Variant
What are the epigenetic sources of variation?
> DNA mathylation
> Chromatic protein modification
What did Bae et al (2014) find?
They provided evidence for a mechanism underlying the variant expression of GPR56
What is polymicrogyria?
A developmental condition in which the brain develops too many and too small gyri
What did Body et al (2015) discover?
Human-Accelerated Regulatory Enhancer 5 (HARE5)
What did Body et al (2015) discover?
Human-Accelerated Regulatory Enhancer 5 (HARE5)