Neuroembryology Flashcards

1
Q

Formation of Neural tube

A

Neurulation

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2
Q

T or F:
About the 16th day, the neural plate invaginates along its central axis to form a longitudinal median neural groove, which has neuralfolds on each side

A

F

18th Day

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3
Q

As the neural folds fuse to form neural tube, neuroectodermal cells migrate dorsolaterally to form ______ which soon divides into two cell masses

A

Neural crest

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4
Q

______ gives rise to the cells that forms the PNS and ANS; cranial, spinal & autonomic ganglia

A

Neural Crest

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5
Q

T or F

Neurulation begins during the early part of the 4th week

A

T

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6
Q

T or F:

Cranial 2/3 represents future brain; cranial neuropore closes on the 15th day

A

F

15th day

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7
Q

T or F

Caudal 1/3 represents future spinal cord; caudal neuropore closes 2 days later

A

T

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8
Q

Layers of Neural Tube

A

Ependymal layer
Mantle layer
Marginal layer

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9
Q

T or F

Axons are at first Unipolar;

A

F

Bipolar

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10
Q

Unipolar neurons in the spinal ganglia (DRG) are derived from?

A

neural crest cells

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11
Q

This produces myelin in the PNS.

A

Neurolemmal cells or Schwann cells

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12
Q

T or F
Recent evidence proves that Folic acid / Folate reduces the incidence of NTD’s by as much as 70% if 200 mg is taken dailybeginning 3 months prior to conception and continuing throughout gestation

A

F

400 mg

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13
Q

Type of Spina Bifida which contains meninges w/ CSF.

A

Spina Bifida with Meningocele

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14
Q

Fusion of the neural folds in the cranial region and closure of the rostral neuropore form how many primary brain vesicles?

A

Three

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15
Q

Prosencephalon divides into _____ and ______

A

Telencephalon

Diencephalon

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16
Q

Calvaria and brain are small but the face is normal size; grossly mentally retarded because brain is underdeveloped

A

Microencephaly

17
Q

Failure of the cephalic part of the neural tube to close during the 4th week of dev’t

A

Exencephaly

18
Q

Associated with acrania (absence of calvaria)

A

Meroanencephaly

19
Q

2 Types pf Hydrocephaly

A

Obstructive or noncommunicating

Nonobstructive or communicating