Neuroembryology Flashcards
Formation of Neural tube
Neurulation
T or F:
About the 16th day, the neural plate invaginates along its central axis to form a longitudinal median neural groove, which has neuralfolds on each side
F
18th Day
As the neural folds fuse to form neural tube, neuroectodermal cells migrate dorsolaterally to form ______ which soon divides into two cell masses
Neural crest
______ gives rise to the cells that forms the PNS and ANS; cranial, spinal & autonomic ganglia
Neural Crest
T or F
Neurulation begins during the early part of the 4th week
T
T or F:
Cranial 2/3 represents future brain; cranial neuropore closes on the 15th day
F
15th day
T or F
Caudal 1/3 represents future spinal cord; caudal neuropore closes 2 days later
T
Layers of Neural Tube
Ependymal layer
Mantle layer
Marginal layer
T or F
Axons are at first Unipolar;
F
Bipolar
Unipolar neurons in the spinal ganglia (DRG) are derived from?
neural crest cells
This produces myelin in the PNS.
Neurolemmal cells or Schwann cells
T or F
Recent evidence proves that Folic acid / Folate reduces the incidence of NTD’s by as much as 70% if 200 mg is taken dailybeginning 3 months prior to conception and continuing throughout gestation
F
400 mg
Type of Spina Bifida which contains meninges w/ CSF.
Spina Bifida with Meningocele
Fusion of the neural folds in the cranial region and closure of the rostral neuropore form how many primary brain vesicles?
Three
Prosencephalon divides into _____ and ______
Telencephalon
Diencephalon
Calvaria and brain are small but the face is normal size; grossly mentally retarded because brain is underdeveloped
Microencephaly
Failure of the cephalic part of the neural tube to close during the 4th week of dev’t
Exencephaly
Associated with acrania (absence of calvaria)
Meroanencephaly
2 Types pf Hydrocephaly
Obstructive or noncommunicating
Nonobstructive or communicating
