Neurodevelopment + Attention Disorders Flashcards

1
Q

Females with ADHD present more commonly with which subtype; why is this a problem?

A
  • Inattentive subtype
  • Less disruptive behavior in females may contribute to referral bias causing under identification and lack of tx
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2
Q

What is the tourette’s syndrome triad?

A
  • Tics
  • ADHD
  • Obsesseive compuslive sx’s (OCS)
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3
Q

Which other disorder needs to be considered in both the initial assessment and ongoing management of children with ADHD?

A

Chronic Tic Disorder

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4
Q

ADHD is an information processing dysfunction where in the brain; primarily due to deficinecy of which 2 NT’s?

A
  • Within prefrontal cortex
  • Deficiency of dopamine and norepinephrine
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5
Q

According to the DSM-5 how many sx’s should a child vs. patient >17 y/o have for making dx of ADHD?

A
  • Children: should have 6 or more
  • Adults: should have at least 5 sx’s
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6
Q

According to the DSM-5 what are 9 sx’s of the inattentive type of ADHD?

A
  • Fails to give close attention to details or make careless mistakes
  • Difficulty sustaining attention
  • Does not appear to listen
  • Struggles to follow through on instructions
  • Difficult with organization + loses things + easily distracted
  • Avoids or dislikes tasks requiring a lot of thinking
  • Is forgetful in daily activities
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7
Q

According to the DSM-5 what are the sx’s that fit the hyperactive type of of ADHD?

A
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8
Q

What are the clinical practice guidelines for treating preschool-aged children (4-5 years of age) with ADHD?

A
  • Prescribe evidence-based parent- and/or teacher-administered behavior therapy as the 1st line tx
  • Prescribe methylphenidate if the behavior therapy does not provide significant improvement and the child continues to have moderate to severe sx’s
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9
Q

What are the clinical practice guidelines for treating elementary school-aged children (6-11 years of age) with ADHD?

A
  • Prescribe FDA approved meds for ADHD and/or evidence-based parent and/or teacher-administered behavior therapy as tx for ADHD
  • Preferably both medication and behavior therapy should be used together
  • Evidnce is particularly strong for stimulant medications
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10
Q

What is a potential AE associated with Bupropion?

A

↑ risk of seizure

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11
Q

Which stimulant used for ADHD is a re-uptake inhibitor of catecholamines AND also releases catecholamines?

A

Amphetamines

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12
Q

Intellectual disability leads to…

A

intellectual deficiets and impairement of adaptive functioning

3 requirements:

  1. Deficits in intellectual functions
  2. Deficits in adaptive functioning that result in failure to meet developmental and sociocultural standards
  3. Onset during developmental period
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13
Q

Speech vs. Language vs. Communication Disorders

A
  1. Speech: difficulty with speech sound production
  2. Language: difficulty with acquisition and use of language
  3. Communication: disturbances in normal fluency and time patterning of speech (difficulty with sequencing)

onset for all occurs early developmental period

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14
Q

How does autism manifest?

A
  1. Deficits in social-emotional reciprocity
  2. Deficits in nonverbal communicative behaviors used for social interaction
  3. Deficits in developing, maintaining, and understanding relationships
  4. Restrictive, repetitive patterns of behavior (at least two):
    1. Stereotyped or repetitive motor movements, use of objects, or speech
    2. Insistence on sameness, inflexible routines
    3. Highly fixated interests
    4. Hyper or hypo reactivity to sensory input
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15
Q

What is the most important behavioral intervention for cases of autism?

A

education and support for family members + teachers

teach about parallel processing

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16
Q

What medications are approved for ASD?

A

risperidone and aripiprazole for the irritability and agitation

17
Q

What is Tourette’s Triad

A

OCS

ADHD

Tics

18
Q

Dx criteria for chronic tic disorder

A

motor OR vocal tics

wax and wane in frequency, but persist more than one year

onset before age 18

*higher in kids with ADHD

19
Q

The tx for ADHD with stimulants can have what effect on associated tics?

A

increased

20
Q

The executive functioning is dysfunctioning in ADHD due to…

A

located in prefrontal cortex

def of DA and NE

21
Q

What tests can be useful in ADHD dx?

A
  1. Test of Variables of Attention (TOVA)
  2. Conners Continuous Performance Test (8 y/o+)
22
Q

What are some alternative medications (other than stimulants) for ADHD?

A
  1. Guanfacine, Clonidine: alpha 2 agonists; modulate noradrenergic tone in PFC
  2. Bupropion
  3. Atomoxetine: inhibits presynaptic NE reuptake; used with caution in CV risk
  4. Modafinil: adults only, inhibits DA reuptake
23
Q

What is developmental coordination disorder?

A

coordinated motor skills below expected

manifests as clumsiness, inaccuracy in motor performance…

significant enough to interfere with academics, daily life…

24
Q

What condition is marked by repetitive, seemingly driven, and apparently purposeless motor behavior?

A

stereotypic movement disorder

25
Q

Criteria for Tourette’s Disorder

A

multiple motor AND verbal tics present (though do not have to be at the same time) for over one year

onset prior to age 18

comorbidities: ADHD, OCD, anxiety, mood disorders, risk of suicide, disruptive behaviors, learning disabilities, sleep disorders