Neurodevelopment Flashcards
Meroancephaly
Anencephaly
Spina Bifida
Exencephaly
Folic Acid during pregnancy
Example of Segmentation
3 Primary and 5 Secondary Vesicles
Telencephalon, Diencephalon, Mesencephalon, Metencephalon, Myelencephalon
Otx2 role in anterior posterior neural structure. Disease caused by absence.
Wnt signaling role in rostral caudal
FGF 8 role in Anterio-posterio patterning.
Interaction of Pax6 and Emx2
Hox Gene function
Two inductive cues for dorsoventral axis
Holoprosencephaly
Disease and Cause
SHH Mechanism of patterning dorsal-ventral
Two mechanisms of cell differentiating
4 Major types of neural crest cell migratory pathways
Chicken Quail study - Nueral Crest Cell Purpose
Development of Cortical Layers - unique maturation
Migration of inhibitory neurons
Failure of GABAnergic neuron migration effect
Lissencephaly - mutation that causes this
Lis1
Cause of double layering in neuronal migration
DcX Tubulin Mutation
End anatomy of growing Neuron. - Two parts to this feature
Long Range Cues for Guidance
Short Range Cues for Guidance
General Mechanism - axon guidance
Effect-Loss of robo-3 in Mauthner
Effect of robo-3 mutation in humans
Sperry Frog outcome - growing back to original places or new places
Attractants and Repellents in eye for axon guidance.
Where is EphB expressed
Where is EphrinA expressed
How does motor activity affect motor neuron formation
What are neurotrophins
Post-synaptic cell role in trophic factors
NGF role w sympathetic neurons
Neuron competition - effect
Which neurons do best
The Largest and Earliest
Ventricles derived from
