Neurodevelopment 2

Question 1

___ ___: half way point that divides our neural tube into a dorsal and ventral part

Answer 1

sulcus limitans

Question 2

dorsal is ___ and ventral is ____

Answer 2

sensory

motor

Question 3

___ ___: secreted signaling molecule; initially expressed in the notochord

Answer 3

sonic hedgehog

Shh

Question 4

___ ___ ___: secreted signaling proteins with a variety of functions; expressed in ectoderm

Answer 4

bone morphogenic protein

Question 5

Shh is ___ and expressed in ____ and ____

Answer 5

ventral
notochord
floorplate

Question 6

BMPs are ___ and expressed in ___

Answer 6

dorsal

epidermis

Question 7

floor plate is ___ ___ induced by notochord to secrete ___

Answer 7

neural tissue

Shh

Question 8

Floorplate is ____ inducing and roofplate is ___ inducing

Answer 8

sensory

motor

Question 9

in the neural tube both Shh and BMP are released from both directions, when there is an equal concentration in the middle the ___ ___ are produced

Answer 9

autonomic nerves

Question 10

pial surface comes into contact with the ___ matter

Answer 10

pia

Question 11

___ zone: area around the ventricle; a lot of pluripotent cells becoming neural and then migrating

Answer 11

ependymal zone

Question 12

___ zone contains a lot of cell bodies and cells establish connections; cells sprout long processes that reach out into the marginal zone

Answer 12

mantle

Question 13

___ zone contains axons of cell bodies

Answer 13

marginal

Question 14

____: progenitors become radial glia and then can develop into either neurons or glia

Answer 14

neurogenesis

Question 15

stem cells have __ fate

Answer 15

no

Question 16

neuroepithelial cells have 2 fates

Answer 16

stay the same

radial glial cell

Question 17

radial glial cells have 3 fates

Answer 17

stay the same
neuron
glia

Question 18

glia cells have 3 fates

Answer 18

oligodendrocyte
astrocyte
ependymal

Question 19

whether or not a cell becomes a neuron or glia is largely based on _____ in development

Answer 19

WHEN; time

Question 20

alar plate is ___ and basal plate is ___

Answer 20

dorsal

ventral

Question 21

central canal is in the ___ part of the spinal cord and contains ___

Answer 21

ventral

CSF

Question 22

marginal zone becomes the ___ ___ and mantle zone becomes the ____ ___

Answer 22

white matter

grey matter

Question 23

___ ___ spreads out and becomes mostly ependymal… choroid plexus

Answer 23

roof plate

Question 24

__ ___ becomes sensory nuclei for cranial nerves 7-10

Answer 24

alar plate

Question 25

alar plate becomes ___ nuclei for cranial nerves ___ to ____

Answer 25

sensory

7-10

Question 26

____ ___ becomes motor nuclei for cranial nerves 7-12

Answer 26

basal plate

Question 27

basal plate becomes ___ nuclei for cranial ___ to ___

Answer 27

motor

7-12