Neurochemistry And Neurophysiology Of Nerve Transmission Flashcards

1
Q

List the 5 parts of a cell

A
Soma (cell body) 
Dendrites 
Axon
Myelin sheath 
Presynaptic terminals
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2
Q

What’s the difference between efferent and afferent?

A

Afferent carries info to

Efferent carries info away

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3
Q

Which 2 places are clusters of cell bodies found?

A

NS nucleus

PNS ganglion

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4
Q

Which 2 places will you find clusters of axons?

A

NS tract

PNS nerve

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5
Q

What are micro glia?

A

Removes waste materials and microorganism virus/fungi

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6
Q

Oligodendrocytes and Schwann cells build myelin sheath, true or false

A

True

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7
Q

What’s the radial glia?

A

They guide migration of neurons and growth of axon

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8
Q

List 3 ways our body protects the NS?

A

Skull
Backbone
Blood-brain barrier

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9
Q

What can get through blood-brain barrier?

A

O2 and co2

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10
Q

What’s a nerve impulse?

A

Neurons conduct info via electrical impulses

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11
Q

What do the glia do?

A

Receive and transmit info and support neurons

Remove waste materials

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12
Q

What is the resting potential?

A

When more negative inside cell than outside

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13
Q

What chemicals are present in negative

A

Chloride and protein

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14
Q

What chemicals are present in positive?

A

Sodium and potassium

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15
Q

What are the 4 steps of action potential?

A

1) concentration gradient
2) electrical gradient
3) membrane permeability
4) sodium potassium pump

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16
Q

What is the action potential?

A

Response of neutron to stimulation above certain threshold which results in depolarisation, Neuron becomes less negative

17
Q

What’s the all or nothing law?

A

The amplitude and velocity of AP are independent of the initiating stimulus

18
Q

What happens at AP exactly?

A

Na enters cell
K leaves cell
Na and k pump restores original ion distribution

19
Q

What can’t happen immediately after AP?

A

Cell cannot produce another AP (refractory period)

20
Q

Where does the AP begin?

A

Axon hillock

21
Q

What 2 things help the conduction speed?

A

Avon diameter and myelin sheath

22
Q

Name the 3 parts of the synapse?

A

Presynaptic terminal
Synaptic cleft
Post synaptic neurons

23
Q

What’s the key in lock system?

A

Specific receptors for specific neurotransmitter

24
Q

What are ion tropic receptors?

A

Fast, short glutamate GABA for vision and hearing

25
What are metabotropic receptors?
Slow, G protein, for hunger and thirst
26
What is temporal and spatial summation?
Neurons conduct info through APs. APs can be initiated by temporal or spatial summation if excitatory post synaptic potentials (EDSPs)
27
Which drug is psychoactive?
Cocaine
28
Describe cocaine
Dopamine and noropinephrine agonist - euphoria and appetite lost
29
What do benzodiazepines do?
Reduce anxiety and induce sleep | GABA agonist