Neuroanatomy Flashcards
What composes white matter?
Myelinated axons
What composes grey matter?
Neuronal cell bodies
Where is white matter found?
Spinal cord (outside) Brain (inside)
What are the names of the different tracts present?
Commissural
Projection
Association
Within the CNS, what are a collection of cell bodies called?
Nucleus
Within the PNS, what are a collection of cell bodies called?
Ganglion
Where are the lateral ventricles found?
Cerebral hemispheres
What lies next to the 3rd ventricle?
Thalamus
Where does the cerebral aqueduct lie?
Midbrain
Where does the 4th ventricle lie?
Between pons, medulla & cerebellum
Between which layers is the CSF found?
Pia
Arachnoid
What produces CSF?
choroid plexus
Where is CSF absorbed?
Arachnoid villi into sagittal sinus
Where do the internal carotid arteries enter the skull?
Carotid canal
What artery do the vertebral arteries branch off?
Subclavian
Through which foramen do the vertebral arteries go through?
Foramen magnum
What are the main contributing factors to the Circle of Willis?
ICA
Basilar artery
What is the function of the Circle of Willis?
Protective mechanism which allows circulation to be maintained to the brain
What area of the brain does the Circle of Willis supply?
Cerebral hemispheres
The ICA give branches to which arteries?
ACA
MCA
Post communicating
Which arteries of the C o W supply the largest area of the cerebrum?
ACA
MCA
What do the 2 vertebral arteries combine to form?
Basilar artery
What does the vertebra-basilar system supply?
Brainstem
Cerebellum
What does the basilar artery divide into?
PCA
Which artery supplies the medial aspect of the cerebrum?
ACA
Which artery supplies the occipital lobe? If it is occluded what can it lead to?
PCA
Visuocortical blindness
Between which 2 layers do the venous sinus lie?
Dural folds
What vein do the venous sinus drain into?
IJV
What does the neural tube form from?
Ectoderm
What is another name for the forebrain?
Prosencephalon
What is another name for the midbrain?
Mesencaphalon
What is another name for the hindbrain?
Rhombencephalon
What does the Prosencaphlon form?
Telencephalon
Diencaphalon
What does the Mesencephalon form?
Midbrain
What does the Rhombencephalon form?
Metencephlon
Myencephalon
What forms the brainstem?
Midbrain
Pons
Medulla oblongata
Which cranial nerves arise from the brainstem?
III-XII
What does the medulla continue as?
Spinal cord
What is the name of the medullary area where decussation of fibres occurs?
Pyramids
What lies lateral to the pyramids at the medulla
Olives
What connects the medulla & cerebellum?
Inferior cerebellar peduncles
What cranial nerves arise from the medulla?
IX, X, XI, XII
What connects the pons to the cerebellum?
Middle cerebellar peduncles
Which cranial nerves originate from its surface?
V, VI, VII & VIII
What is 2 structures are present at the midbrain?
Superior & Inferior colliculi
What is the function of the superior colliculi?
Visual reflex
What is the function of the inferior colliculi?
Auditory reflex
What peducles are present at the midbrain?
Cerebral peduncle
Superior cerebellar peduncle
Which cranial nerves originate from the midbrain?
III, IV
Which cranial nerve is the only nerve to originate posteriorly?
Trochlear nerve (IV)
What are the name of 2 nuclei found in the midbrain?
Substantia niagra
Red nucleus
What disease is the substantia niarga associated with?
Parkinsons disease
What are the folds & ridges called at the cerebellum?
Sulci & folia
Each cerebellar hemisphere is composed of which lobes?
Anterior
Posterior
Flocculonodular
What connects the 2 cerebellar hemispheres?
Vermis
What matter are the cerebellar peduncles composed of?
White matter
Where is the grey/white matter found on the cerebellum?
Grey matter (surface) White matter (deep)
What is the risk associated with increased intracranial pressure & cerebellar tonsils?
Herniation of cerebellar tonsils
What is the function of the cerebellum?
Coordination & balance
If there is an abnormality at the cerebellum, what is a sign that could be observed?
Ataxia
What are the structures of the diencephalon?
Thalamus
Hypothalamus
Pineal gland
Pituitary gland
What is the function of the thalamus?
Sensory relay centre
What is the role of the hypothalamus?
Homeostatic control of temperature, thirst, appetite, sleep/wake cycle & endocrine control.
What is the function of the brainstem?
Control vital signs (respiratory centre)
What are the 2 divisions of the motor (efferent) pathway?
Somatic
Autonomic
What are the 2 divisions of the autonomic pathway?
Sympathetic
Parasympathetic
What is the function of neutrons?
Carry action potentials
What is the cytoplasm in the neuronal cell body called?
Perikaryon
What is the function of myelin sheath?
Insulates axon, increasing speed of conduction
What cells form the myelin sheath?
Schwann cells (PNS) Oligodendrocytes (CNS)
What happens to myelin in MS?
Demyelination of nerves
Which tract do sensory fibres ascend in the spinal cord?
Dorsal column
Which tract carries pain fibres up to the brain?
Spinothalamic tract
What are the different tracts which carry motor fibres down the spinal cord?
Lateral & anterior corticospinal tract
Rubrospinal tract
Where are pseudounipolar neurons found?
Sensory afferent neurons
Where are bipolar neutrons found?
Retinal nerve fibres
Olfactory mucosa
What is the most common type of neuron?
Multipolar
Which cells line the central canal & produce CSF?
Ependymal cells
What are the types of glial cells found within the CNS?
Microglia cells
Oligodendrocytes
Astrocytes
What are the factors which compose the BBB?
Tight junctions at endothelium
Basal lamina
Astrocyte projections
Where is the BBB absent?
Hypothalamus
Posterior pituitary
In order for a drug to cross the BBB, what does it have to be?
Lipid soluble
OR USE VECTORAL TRANSPORT
How many horns do the lateral ventricles have?
3 - anterior, posterior & inferior horns
Which meningeal layer is vascularised?
Pia mater
Where is CNS found? (meninges)
Subarachnoid space
What is the function of CSF?
Protects & nourishes the brain
What is the name of the collection of neuronal cell bodies deep within the cerebral hemispheres?
Basal ganglia
What is the name of the fissure between the 2 cerebral hemispheres?
Median longitudinal fissure
What is the function of the corpus callosum?
Connects the 2 cerebral hemispheres
What lies in front/ behind the central sulcus?
Primary motor cortex (precentral gyrus)
Primary somatosensory cortex (postcentral gyrus)
What does the lateral sulcus separate?
Frontal lobe & Temporal lobe
What sulcus divides the parietal & occipital lobes?
Parieto-occipital sulcus
What is the name of the sulcus which runs above the corpus callosum?
Cingulate sulcus
In which lobe is the hippocampus found?
Temporal lobe
What are the 52 areas of the brain called?
Brodmann areas
Which hemisphere, dominant or non-dominant usually controls movement?
Dominant
Which cerebral hemisphere tends to be the dominant side?
Left hemisphere
What area is the precentral gyrus?
Area 4
What does Broca’s area control? What area?
Motor speech
Area 44,45
What is the motor/ sensory map depicted at the pre/pos central gyrus?
Homunculus
What are the areas of the post-central gyrus?
3, 1, 2
Which cerebral lobe contributes to language function?
Parietal lobe (dominant hemisphere)
When there is a parietal lobe lesion, what is observed?
Hemisensory neglect
Agraphia, acalculia, agnosia
What cortex is found at the temporal lobe? Area?
Primary auditory cortex
41,42
What auditory association area is found at the dominant temporal lobe? Function?
Wernickes area
Important for understanding spoken word
Which lobe receives fibres from the olfactory tract?
Temporal lobe
Where is the Primary visual cortex found?
Occipital lobe (calcarine sulcus)
Which surface of the cerebrum is the limbic system found?
Medial surface
What is aphasia?
Problem with speech due to damage to brain
If there is damage to Brocas area, what type of aphasia will be observed?
Expressive aphasia
unable to speak, paralysis
If there is damage to Wernickes area, what type of aphasia will be observed?
Receptive aphasia
Will talk away saying nonsense words
What is the internal capsule composed of?
Projections fibres (white matter tracts)
Where does the internal capsule derive its blood supply?
MCA
What composes the basal ganglia?
Caudate nucleus, putamen & globus pallidus
What composes the lentiform nucleus?
Putamen & globus pallidus
What part of the basal ganglia is in contact with the lateral ventricle?
Caudate nucleus
What lies in contact with the 3rd ventricle?
Thalamus
What is the main function of the basal ganglia?
Initiation & termination of movement
What is the basal ganglia also referred to as?
Extrapyramidal system