Neuro PD not done Flashcards

0
Q

This without the basal ganglia or cerebellum they can still move, but it just has to be alot

A

Slower, it would seem alot like taxia.

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1
Q

Primary motor and non primary cortex, it is modulated, even before the basalmganglia or the cerebellum.

A

.

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2
Q

By cerebellum it is like ataxia that they widen the base of support to not fall.

A

.

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3
Q

Without the basal ganglia it is even worse than the cerebellar issue.

A

.

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4
Q

A baby walking, they go fast and they either fall forward or they fall backwards.

This is mostly primary and non-primary motor cortex.

A

.

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5
Q

Non-primary motor cortex is

A

The parietal and working memeory and it is also call the suplemental.

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6
Q

From the PMC to the basal ganglia what is in the between

A

Thalamus

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7
Q

If the thalamus sendsalot of information it is excited?

A

Yes

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8
Q

The basal ganglia modulates the PMC signal and then sends that to the

A

Spinal cord

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9
Q

The ______ also besides the basal ganglia sends the PMC’s signal to the spinal cord.

A

Cerebellar.

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10
Q

The NPMC, non-primary motor cortex, also does what?

A

Modulates the information.

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11
Q

If you knock out the basal ganglia you loose…

A

Whatever control you would have have had on the thalamus.

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12
Q

The ________ is the key playert hat gets the information to the brainstem.

A

The Thalamus.

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13
Q

Basal ganglia loops, can it be that we do not have it?

A

No

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14
Q

What are the two things that the basal ganglia can do?

A

Over stimulating the thalamjs, to over inhibit it, to cause PD,

Or understimulate it and it is overexcited.

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15
Q

Motor cortex is ontop and in the center is

A

The globus pallidase

16
Q

Mc on top, globus pallidase is in the center, and then we have the?

A

Striatum

17
Q

The striatum is made of

A

Claudate nucleus and putamin.

18
Q

Mc, globus pallidase, thalamus, and striatum(which the caudate nucleas and putamin)

A

.

19
Q

Neurotransmitters.

A

GABA, ths whole thing, which is inhibitory.

20
Q

Key player in neurtransmitter for the direct route is the …

A

GABA.

21
Q

GLobus Pallidase does what to the thalamus?

A

Inhibits

22
Q

The thalamus is inhibitory or excitatory?

A

Excitstory

23
Q

Caudate and Putamin are supposed to?

A

Send out GABA an inhibitory neurotransmitter.

24
Q

The activation of the STRIATUM which will release GABA to the GP, and now the GO will not release its GABA and so the Thalamus is overactive.

A

.

25
Q

What inhibits the thalamus and with which neurotransmitter?

A

The GP and with GABA.

26
Q

The striatum is what will end up controlling the Thalamus?

A

Yes,

27
Q

If the STRIATUM is inhibited then the GP is not inhibited and so the thalamus will get inhibited.

A

.

28
Q

If the striatum is active, the it activates the GP, which inhibits the thalamus, which has more excitatory.

A

.

29
Q

Striatum is inhibited so will the thalamus be inhibited.

If the striatum is activated the thalamus will also get activated.

A

.

30
Q

The inhibitory the indirect loop.

A

.

31
Q

Subthalmic nuclei

A

Is under the thalamus is the main player of the indirect route.

32
Q

The subthlamic nuclei is inhibitory?

A

Yes

33
Q

Glumtamate excites or inhibits?

A

Excites

34
Q

The STN is to work on the GP which we did say affects the thalamus.

A

.

35
Q

Alcohol is a depressant, so it activates the

A

STN, which uses GLUTAMATE to wxcite the GP which inhibits the THALAMUS which now there is less excitation from the THALAMUS to the MOTOR CORTEX.

36
Q

With PD the person is down to ____% of their usually dopamine production.

A

20

37
Q

If it is not an underproduction it is ________ that causes PD?

A

It is the lack of ability to be able to use dopamine.