Neuro Limb Extras Flashcards
UMN lesion; tone, power, reflexes, plantars, coordination, other features
- Tone: spastic
- Power: reduced
- Reflexes: brisk
- Plantars: up
- Coordination: reduced
- Other features: clonus
Extrapyramidal lesion; tone, power, reflexes, plantars, coordination, other features
- Tone: rigid
- Power: normal
- Reflexes: normal
- Plantars: down
- Coordination: reduced
- Other features: TRAP
Cerebellar lesion; tone, power, reflexes, plantars, coordination, other features
- Tone: reduced
- Power: normal
- Reflexes: normal
- Plantars: down
- Coordination: very reduced
- Other features: VANISHED
Pain and temperature pathway and pathology Ddx
Pathway: spinothalamic
Ddx: syringomyelia
Vibration, proprioception and fine touch pathway and pathology Ddx
Pathway: dorsal column
Ddx: tabes dorsalis, b12/folate deficiency (subacute combined degeneration of the cord - SCDC)
Syringomyelia - pathophysiology, signs
Pathophysiology: expansion of central canal due to CSF blockage
Signs:
- Loss of pain and temperature sensation (arms, shoulder and upper body - ‘Cape like’)
- LMN signs in upper limbs
- Spastic paraparesis in lower limbs
- Dorsal column sensation affected if severe
- Syringobulbia if syrinx extends into brainstem
Erb’s palsy signs
Injury to C5-7 - shoulder dystocia during birth
- Sensory loss down lateral arm
- ‘Waiter’s tip’ position (shoulder adducted, arm internally rotated, forearm pronated)
Klumpke’s palsy
Injury to C8-T1 - excessive arm traction during birth
- Sensory loss in medial forearm and hand
- Complete claw hand
- Wasting of small muscles in hand
- Horner’s syndrome may coexist
- Sensory loss down lateral arm
- ‘Waiter’s tip’ position (shoulder adducted, arm internally rotated, forearm pronated)
Erb’s palsy
- Sensory loss in medial forearm and hand
- Complete claw hand
- Wasting of small muscles in hand
Klumpke’s palsy
Tone: reduced
Power: reduced
Reflexes: reduced
Plantars: down
Coordination: normal
Other features: wasting, fasiculations
LMN lesion
Tone: spastic
Power: reduced
Reflexes: brisk
Plantars: up
Coordination: reduced
Other features: clonus
UMN lesion
Tone: rigid
Power: normal
Reflexes: normal
Plantars: down
Coordination: reduced
Other features: TRAP
Extrapyramidal lesion
Tone: reduced
Power: normal
Reflexes: normal
Plantars: down
Coordination: very reduced
Other features: VANISHED
Cerebellar lesion
LMN lesion; tone, power, reflexes, plantars, coordination, other features
Tone: reduced
Power: reduced
Reflexes: reduced
Plantars: down
Coordination: normal
Other features: wasting fasiculations
Unilateral leg weakness Ddx - UMN
- Stroke
- Tumour
- MS
Unilateral leg weakness Ddx - LMN
- Root lesion
- Nerve lesion
B12/folate deficiency - subacute combined degeneration of the cord (SCDC) signs
- Spastic paraparesis
- Up going plantar
- Reduced lower limb reflexes
- Dorsal column loss including Romberg
Amyotrophic lateral sclerosis (ALS) signs
Type of MND
- Weakness
- Wasting
- Fasiculation
- Spasticity
- Brisk reflexes
Foot drop Ddx
- Common peroneal nerve palsy
- Stroke
- L4/5 root lesion
- MND
- Charcot-Marie-Tooth syndrome
Bilateral leg weakness Ddx - acute/progressive (unlikely in OSCE)
- Acute spinal cord compression (UMN)
- Cauda equina syndrome (LMN)
- Guillain Barre syndrome (LMN)
Bilateral leg weakness Ddx - UMN
- Sagittal sinus lesion (exclusively motor signs)
- Bilateral strokes
- Syringomyelia (with upper limb signs)
- Cord trauma
- Cord compression (extramural tumour, disc prolapse, spondylosis)
- Intrinsic cord disease (tumour, vascular myelopathy, MS) Check sensory level for 4-6 LMN at level of 5
Bilateral leg weakness Ddx - LMN
- Polio
- Mostly motor peripheral neuropathy (GB, lead poisoning, Charcot Marie tooth)
- Mixed peripheral neuropathy (diabetic, uraemic, vitamin def., paraneoplastic, alcoholic)
Peripheral sensory neuropathy Ddx
- Mononeuropathies - I.e. Compression neuropathy e.g carpel tunnel
- Diabetic peripheral neuropathy
- Demyelinating neuropathy
- Neuritis - B12 deficiency, shingles
Guillain barre - cause, observation
Cause - cross reactivity (anti-ganglioside antibodies)
Observation - progressive, idiopathic, symmetrical weakness, and loss of deep tendon reflexes. Maximal intensity at 4 weeks
Charcot Marie Tooth - cause, observation
Cause: Genetic disease
Observation: gradual loss of muscle bulk and sensation.
- Foot drop
- Loss of sensation
- Neuropathic pain
Charcot Marie Tooth - Ix
- Nerve conduction studies
- Nerve biopsy
- Genetic testing