Abdominal Flashcards
Ascites Ddx - exudate
(Protein > 30g/L)
- Infection (TB, pyogenic infection)
- Inflammation (pancreatitis)
- Malignancy (luminal, pancreas, liver, ovarian, lymphoma)
- Lymphoedema
- Hypothyroidism
Aetiology of ascites in CLD
- Portal HTN
- Hypoalbuminaemia
- Salt and water retention (RAAS Activation)
Gynaecomastia Ddx
- Physiological (puberty,elderly)
- Testicular failure
- Increased estrogen
- Drug-induced
Gynaecomastia - Testicular failure Ddx
- Klinefelter’s syndrome
- Viral orchitis/testicular trauma
- Haemodialysis
Gynaecomastia - increased oestrogen Ddx
- Chronic liver disease
- Thyrotoxicosis
- Oestrogen-secreting tumour
Gynaecomastia - Drug-induced Ddx
DISCO MTV
- Digoxin
- Isoniazid
- Spironalactone
- Cimetidine/calcium channel blocker
- Osteogens
- Methyldopa
- Tricyclics
- Verapamil
Hepatomegaly Ddx
BI INCH
- Biliary
- Infection
- Infiltrative
- Neoplastic
- Congestion (venous)
- Haematological
Hepatomegaly - infection Ddx
- Hepatitis*
- EBV*
- Malaria*
- Liver abscess
* causes hepatosplenomegaly
Hepatomegaly - neoplasm Ddx
- Primary
2. Metastatic
Hepatomegaly - congestion (venous) Ddx
- RHF
- Tricuspid regurgitation
- Budd-Chiari syndrome
Hepatomegaly - haematological Ddx
- Lymphoma/leukaemia
- Myelofibrosis
- Sickle-cell anaemia
All these cause hepatosplenomegaly
Hepatomegaly - infiltration Ddx
- Sarcoid/Amyloid*
- Haemochromotosis
- Fatty liver
* causes hepatosplenomegaly
Hepatomegaly - biliary Ddx
- PBC
2. PSC
Splenomegaly - mild Ddx
GRIP
- Glandular fever
- RA (Felty’s syndrome)
- Infective Endocarditis
- Pernicious anaemia
Splenomegaly - moderate Ddx
- Lymphoma / leukaemia
- Portal hypertension
- Haemolytic anaemia
Splenomegaly - massive Ddx
- Malaria
2. Myeloproliferative (myelofibrosis, CML)
Smooth liver edge Ddx
- Venous congestion
2. Fatty infiltration
Knobbly liver edge Ddx
- Metastases
2. Cysts
Pulsating liver dx
TR
Tender liver edge Ddx
- Hepatitis
2. RHF
Liver bruit Ddx
- HCC
- AV malformation
- TIPSS
Peripheral IBD Signs
- Finger clubbing
- Mouth ulcers (especially crohn’s)
- Eyes - episcleritis, conjunctivitis
- Skin - erythema nodosum, pyoderma gangrenosum
- Joints - seronegative spondyloarthropathy
Pancreatitis - causes
GET SMASHED
- Gallstones
- Ethanol
- Trauma
- Steroids
- Mumps
- Autoimmune
- Scorpion envenomation
- Hyperlipidaemia/parathyroidism
- ERCP/surgey
- Drugs
Pancreatitis risk factors
- Gallstones
- Ethanol
- FHx of pancreatitis
- High TGs
- Smoking
- CF
- Medications - some ABx and oestrogen
- Congenital - pancreas divisum
Biliary colic Ddx
- Acute cholecystitis
- Ascending cholangitis
- Pancreatitis
Biliary colic investigations
- LFT (raised ALP and bilirubin)
- lipase/amylase normal (Ddx pancreatitis)
- Urine normal
- Gallbladder USS - 95% sensitive
- CXR - normal
Biliary colic - management
- Analgesia - paracetamol, NSAIDS, opioids
- Antiemetics - omeprazole
- Laparoscopic cholecystectomy (definitive)
- Shockwave lithotripsy
Peptic ulcer disease - causes
- NSAID usage - up to 20% in long term users
- H. Pylori -90%
- Acid induced
- Chronic disease I.e. COPD, CF, CKD, cirrhosis
Peptic ulcer disease - risk factors
- Aspirin, NSAIDs
- Alcohol I.e. Gastritis
- Smoking
- Coffee
- Corticosteroids
Duodenal vs. Gastric ulcer - history
Duodenal - Epigastric pain, relieved by antacids, nocturnal pain
Gastric ulcer - Epigastric pain, relieved by antacids, aggravated by food, may have anorexia, weight loss, N&V
Peptic ulcer disease - red flags
- Age > 50
- Dysphagia
- Early satiety
- Vomiting
- Jaundice
- FHx of gastric cancer
- Weight loss
- GI bleed
Peptic ulcer disease - Ddx
- Cholecystitis
- Pancreatitis
- Appendicitis
- Gastric cancer
- Ischemic bowel if elderly
- IBD
Peptic ulcer disease - investigations
- Trial of PPI
- H. Pylori stool antigen
- Gastroscopy if any red flags
Peptic ulcer disease - management
- Stop NSAIDs
- Start PPI
- Treat H. Pylori (metronidazole, tetracycline. Bismuth, omeprazole)
Peptic ulcer disease - complications
- Perforation
2. Haemorrhage
AAA - risk factors
- Smoking
- FHx
- Atherosclerosis
- HTN
- Age
- Male
AAA - causes
- 25% associated with atherosclerosis
- Aortic dissection
- Ehler’s danlos syndrome
AAA - presentation
75% a symptomatic
- Sudden onset back pain
- Pulsatile mass
- Hypotension
AAA - investigations
- USS - sensitivity is 100%
- CT if obese
- Pre-op evaluation is done by CT/MRI angiogram
AAA - management + indication
Surgical repair
- Pain
- Asymptomatic & >5.4cm or enlarging
AAA - pre-op risk reduction
- Stop smoking
- Beta-blocker
- COPD optimisation
- Renal function optimisations
Types of Gallstone pathology
- Biliary colic - transient cystic duct obstruction
- Cholelithiasis - presence of gallstones
- Cholecystitis - persistent cystic duct obstruction
- Choledocholithiasis - stones in CBD
- Ascending cholangitis - infection of the biliary tract due to bacteria ascending from duodenum
Gallstone - risk factors
- Female, forty, fair skinned, FHx, fat
- High calorie diet
- Associated with obesity, DM, cirrhosis
- HRT, oral contraceptive
Types of gallstones
- Cholesterol
2. Black pigment stones (bilirubin)
Gallstone Ddx
- Hepatitis
- Pancreatitis
- Gastritis
- Peptic ulcer disease
- GORD
- PID
Renal colic - risk factors
- Age
- Male
- Congenital
- Corticosteroids
- Low urine volume
Renal colic - types of stones
- Calcium oxalate
- Calcium phosphate
- Uric acid
- Struvite
- Cysteine
Renal colic - presentation
- Sudden, severe abdominal pain
- Unilateral flank pain (loin to groin)
- N & V
- Haematuria
Renal colic - Ddx
- UTI
2. Acute prostatitis
Renal colic - investigations
- Non-Contrast CT Urogram (gold standard - 95% sensitivity + specificity)
- Abdominal USS - good to rule out stones but not to find them
- Intravenous pyelogram (good if CT not available and not pregnant)
- MSU - haematuria
- Urine culture
- RFT - BUN, creatinine
Renal colic - management
- Analgesia - NSAIDs are highly effective
- Nifedipine or tamsulosin
- Shock wave lithotripsy
- Stent
- Open surgery
- Fluid - prevention
NSAIDs and AKI
- Afferent arteriole constricts with NSAID use (pre-renal failure)
- Interstitial nephritis
- Need to monitor renal function
Triple whammy: NSAID, diuretic, ACEi
Monitor renal function
Splenomegaly - investigations
- FBC
- LFT
- Echo (cardiac cause)
- ESR - RA
- ANA - SLE
- Splenic USS
- Abdominal CT
- Gallium scan (lymphoma or infection)
Internal vs external haemorrhoids
Weakness of connective tissue in anorectal vessels
Internal - above dentate line, painless
External - below dentate line, may be painful
Haemorrhoids - causes
- Constipation - straining
- Diarrhoea
- FHx
- Obesity
- Portal hypertension and ascites
Haemorrhoids - presentation
- Itchiness
- Rectal bleeding
- Rectal pain
- Prolapse
Haemorrhoids - examination
- Inspect
- PR exam
- Anoscopy
Haemorrhoids - Ddx
- Anal fissure
- Abscess
- Rectal fistula
- Cancer
- IBD
- Skin tags
- Rash
Ascites Ddx - transudate
(Protein < 30g/L)
- CLD (75%)
- CHF
- Volume Overload
- Hypoalbuminaemia
- Constrictive pericarditis