Neuro I Flashcards
function of the NS
controls and coordinates the body’s activities to maintain homeostasis
generation of sensory input to be processed
processing incoming data
generation of impulses that control voluntary and involuntary motor functions
storage of information
neurons
are the functional unit of the NS
cell body of neuron
main part of neuron, forms gray matter, center of the neuron
dendtites
recieve nerve impulses, branch like projections, carries impulses towards cell body
3 characteristics of a neuron
excitability
conductivity
influence
excitability
ability to generate an impulse
conductivity
ability to transmit an impulse within itself
influence
ability to influenec other neurons
axon
projects impulses away, found in myelin sheath
myelin sheath
speeds axon transmission, insulates & maintains white matter, nodes of Ranvier
axon with myelin sheath is myelinated or non myelinated
myelinated
multipolar neuron
multiple dendrites one axon
bipolar neuron
one dendrite, one axon
unipolar neuron
one process
lipid gives myelin what?
white color
insoluble in water-so need fat soluble Rx is needed to penatrate myelin sheath
classifications of neurons
structural-defined by the processes they have
functional-diretction of impulses conducted
sensory neurons
transmit nerve impulses toward CNS from peripheral sensory organs
Afferent-towards the brain (CNS)
motor neurons
transmit nerve impulses away from CNS to muscles, glands, organs
Efferent-away from CNS (brain)
Afferent
sensory neurons
Efferent
motor neurons
inter neurons
conduct impulses from one neuron to another
Sensory to motor or motor to sensory
two types of cells in the NS
neurons & neuroglia (glial) cells
Neuroglia cells
purpose: repair, support & protect neurons
more neuroglia than neurons
common source of primary tumors
types of neuroglia cells
astrocytes
ependymal cells
microglia
oligodendrocytes
produce the myelin sheath
astrocytes
found mostly in gray matter, Star of NS,
acumulate where neurons have been damaged
contribute to scar formation (gliosis)
feed neurons, from blood brain barrier
what forms the blood brain barrier
astrocytes
ependymal cells
aid in secretion and regulation of CSF
microglia
remove waste
can damaged nerves regrow
yes
in the CNS-it is limited
in the PNS- slow process
Nerve impulse conduction
travels by electrical transmission along axon and chemical transmission between neurons until it reaches its destination.
an electrical impulse is a result of what
K+ and Na+ ions moving in and out of the cells
Action potential
Our electrical impulses, has 3 states:
resting state
depolarization
repolarization
resting state of action potential
no impulse, increase of K+ within cell and decrease of Na+
depolarization
channels in cell membrance open & Na+ rushes in cell
repolarization
when the Na+ moves back out of cell and K+ moves back in cell
when the impulses reaches the end of the nerve fiber it is then transmitted across the junction between nerve cells at what?
the synapse
saltatory conduction
type of nerve conduction when nerve is myelinated
action potential jumps from one node of Raniver to the next, with saltatory conduction the Na+ and K+ ions only require to move in and out of cells at the Nodes of Tanvier
the synaptic transmission is compossed of what 4 components
presynaptic knob, synaptic cleft, neurotransmitter, and the receptor site
neurotransmitter
chemicals involved in the transmission of an impulse across the synapse
have excitatory or inhibitory
chemicals found in the neurotransmitters
acetylcholine
serotonin
norepinephrine
dopamine
name the two divisions of the nervous system
central and peripheral
the CNS consists of what
brain (cerebrum, brainstem, cerebellum)
and spinal cord
brainstem consists of what
midbrain
pons
medulla
the peripheral nervous system consists of what
12 pairs cranial nerves
31 pairs spinal nerves
autonomic nervous system (sympathetic & parasympathetic)
what are the protective structures of the NS
cranium
-14 facial bones, 8 cranial bones
foramen magnum
large hole, largest hole in skull, where brainstem and spinal cord connect
scalp
outermost layer of protection, fibrous, freely moving
dura mater
outer layer, thickest, toughest
arachnoid
middle layer, thin, delecate, loosly encloses the brain
pia mater
innermost layer, thin, vascular, mesh like
meninges
3, protective membranes that surround the brain and spinal cord
epidural space
between skull & dura mater, above dura mater
subdural space
below dura, between dura & arachnoid
subarachnoid space
between arachnoid & pia mater, holds CSF
name the layers of the protective structures of the nervous system
skin
bone
epidural space
dura mater
subdural space
arachnoid membrane
subarachnoid space
pia mater
brain
falx cerebri
dural fold that separates the 2 cerebral hemisphers
tentorium cerebelli
double dura later fold between the cerebral hemispheres and cerebellum
allows for some expansion
supratentorial
surgery above the tentorium (cerebrum)
infratentorial
surgery below the tentorium
(cerebella)
CSF
cerebrospinal fluid
clear, colorless, odorless
fills ventricles and subarachnoid space of brain and spinal column
no RBC in CSF
what is the purpose of CSF
protects and cusions
shock absorber
what is CSF made of
H2O, protein, O2, CO2, Na, K, Cl, glucose
CSF flow
termed the 3rd circulation,
it is a closed system
absorbed by the arachnoid villi projections
the brain requires ____% of the bodys total oxygen and glucose requirements
25%
Venous drainage of the brain
exits via 2 vascular channels called dural sinuses which empty into the jugular veins
has NO valves, gravity is needed for drainage of blood
where does the arterial supply for the brain enter
foramen magnum
the anterior circulation is supplied by
the common carotid -external & internal carotid
the posterior circulation of the brain is supplied by
the R & L subclavian artery which branhes into R &L vertebral arteries then come together again to make the basiliar artery
circle of willis
allows blood to circulate from one hemisphere to another, acts as a safety valve, protects from occlusion or differential pressures, formed by the basilar artery and internal carotids
blood brain barrier
a pysicological barrier between blood capillaries and brain tissue, made of astrocytes and tight capilaries, protects brain from potential damaging agents, chemicals and toxins
what medications can get through the BBB
lipid souluable
3 divisions of the brain
cerebrum, brain stem, cerebellum
gyrus
convolution (folds) on the surface of the brain, increases surface area
fissure
deep seperations in the cerebral hemispheres
great longitudinal fissure
divides the cerebral hemispher into right and left
cerebrum
largest part of brain, contains nerve centers associated with sensory, motor and higher mental functions
cerebral cortex
outer layer of the brain, it is the gray matter, has billions of neuron cell bodies & dendrites
Made of cell bodies
2 hemispheresof the cerebrum
each hemisphere has 4 lobes
-frontal, parietal, temporal, occipital
have corresponding cortex layer
the white matter of the brain is made up of?
axons
frontal lobe of the brain
contralateral (left controls right, right controls left)
function: ig motor movements, memory, higher cognitive function (problem solving), judgement, broca’s area
Broca’s area is responsible for
expressive speech-ability to form words
damage to this area can cause stuttering, expressive aphasia
can be impaired by trauma or alcohol
cerbral dominacny for 90% of persons is which lobe
left frontal lobe
parietal lobe
primary sensory area
interprets sensory thought-touch, position
body awareness
spatial awareness-ability to comprehen out position in relation to our enviornment (so we are not clumsy)
temporal lobes
auditory reception-hear and interpret sound
Wernicke’s area-reception of speech, ability to understand written & spoken language
receptive aphagia
Wernicke’s area of the brain
temporal lobe
helps with ability to understand writeen and spoken language
damage to the temporal lobe can cause
occipital lobe
primary receptive area for vision and visual association
damage to this area will cause to not understand what is seen
basal ganglia
base/clump of neurons
deep in the hemispheres
responsible for execution, initiation, completion of voluntary movement and autonomic movements (blinking)
diencephalons
area of the brain just above brainstem
includes thalamus, hypothalamus
thalamus
major relay station for all sensations
hypothalamus
regulates autonomic nervous system
effects temperature, fluid balance, reproduction, metabolism, and hunger
limbic system
effects feeding and sexual behaviors and emotional responses
brain stem
connects spinal cord with cerebrum and cerebellum
contains ascending and descending pathways for impulses to go to and from the brain
attachment for crainal cerves III-XII
brainstems 3 main structures
midbrain, pons, and medulla oblongota
what is the medulla oblongata
primary rhythm center, responsible for RR, HR, BP cardiac function
Reticular formation
RAS
special neurons that control the sleep-wake cycle
reticular activating system controls what
attention span, conciousness, damage could cause issues with LOC
cerebellum
located in posterior fossa, above brainstem, below the occipital lope
responsible for fine motor moements, balance, truckal stability
spinal cord
continuious with the brain stem, mass of nervous fibers, extends from C1-L1
what is the spinal cord protected by
meninges (dura mater, arachnoid & pia mater)
and vertebrae
gray matter in the spinal cord
anterior/ventral-wider arms of the H
where primary motor neurons are located, hold motor tracks
the white matter is made up of what?
what does it do?
myelinated nerve tracks, carry messages between the brain and the perioheral muscles
Sensory
afferent messages ascending tracks, messages to the brain
motor
efferent messages, descending tracks, messages go down or away from the brain
ascending tracts of the spinal cord do what
carry sensory input to the brain from the periphery
such as touch, pressure, vibration, and kinesthesia
spinocerebelalr tracts effects what
muscle tension and body positon
nothalamic tracts effects what
temperature and pain