neuro - basics (NTK!) Flashcards

1
Q

gracile and cuneate tract separated by ?

A

post intermediate sulcus

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2
Q

gracile tract starts from ?

A

sacral and coccygeal input

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3
Q

cuneate tract starts from?

A

around T6-T5

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4
Q

in the ‘dorsal column tracts’
sacral region is located more _
cervical region is located more_

vs

in the ‘lateral tracts’ (asc. spinothalamic and desc. corticospinal)
cervical region is located more _
sacral region located more _

A

dorsal column
sacral = medial
cervical = lateral

lateral tracts
cervical = medial
sacral = lateral

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5
Q

BODY - dorsal column medial lemniscus

information for…
pathway..

1st 
origin..
travel..
travel .. *
synapes and terminate..
2nd
origin..
decussate..
travel..
synapse and terminate..

3rd
origin..
terminate

A

Dorsal column medial lemniscus (asending)

  1. upper limb = fasciculus cuneatus (T6-C2)
  2. lower limb = fasciculus gracilis (sacral and coccygeal)
    - touch
    - press
    - proprioception

1st
origin = DRG
travel = asc. or desc. - 1 or 2 levels in the lissaur’s tract
travel up *not decuss yet =
dorsal column fasiculus (gracilus or cuteatus)
synapse and terminate =
ipsi. nucleus gracilis or cuneatus - in (closed medulla)

2nd (a "projection neuron")
origin = closed medulla
decussate = closed medulla
travels up = medial lemniscus 
synapses  and terminate = thalamus (VPL)

3rd
origin = thalamus (VPL)
terminate = cortex (on respected homunculus area of somatosensory cortext/ postcentral gyrus)

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6
Q

BODY - anterolateral / spinothalamic

information for..
pathway..

1st
origin =
travels =*
synapse and terminate =

2nd (a "projection neuron")
origin = 
decussates = 
travels up = 
synapses  and terminate = 
3rd 
origin = 
terminate = 
lower limb-
upper limb
A

anterolateral / spinothalamic (ascending)

    • pain and temp (lateral)
    • crude touch (anterior)

1st
origin = DRG (at level of spinal cord)
travel*= 1 or 2 lvls - lissaur’s tract
synapse and terminate = ipsi. dorsal horn
(rexed lamina lvl 2 = substantia gelatinosa)

2nd (a “projection neuron”)
origin = dorsal horn (at level)
decussates = anterior white commissure (at level)
travels up = spinal lemniscus contralaterlly
(aka sp.thal tract past medulla)
synapses and terminate = thalamus (VPL)

3rd 
origin = thalamus (VPL)
terminate = somatosensory cortex / postcentral gyrus 
(on respected homunculus area)
lower limb - superior cortex 
upper limb - lateral cortex
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7
Q

descending pathways exit through..

A
  • through vental ROOT
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8
Q

subparts of the anterolateral / spinothalamic system ? * 4

A
  1. spino/thalamic
  2. spino/reticular
  3. spino/mesencephalic or spino/tectal
  4. spino/hypothalamic
  5. spinothalamic (direct, main one, pain/temp/crude touch)
  6. spinoreticular ( indirect, c. alertness and arousal in response to stim, activation of the noradrenergic system - termiate brainstem norepinephrin NE neurons and reticular formation)
  7. spinomesencephalic / spinotectal (indirect orients the head and eyes towards stimulus)
  8. spinohypothalamic (pain evoked endocrine response)
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9
Q
name anterolateral system
1st
2nd
3rd 
order neurons
A
1st = sensory neuron 
2nd = interneuron
3rd = relay neuron
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10
Q

BODY - corticospinal tract

*** upper motor neurons / lower motor neurons
information for..
pathway..

1st upper motor neuron
origin= 
travel = 
travel = and become
travel =
decuss = 85% fibres - 
travel in=  
synapse=  
terminate =

2nd - lower motor neuron
orig =
term=

cont. travel ipsi= 15% continue as 
decussate = 
synapse = 
terminate =  
1.
2. 
3.
A

cortico/spinal tract (descending)

    • lateral cortico = appendicular mus
    • anterior cortico = axial mus

85%
1st upper motor neuron
origin= primary motor cortex (precentral gyrus)
travel = internal capsule
travel = cerebral peduncle (become in medulla)
travel = medulla - ‘pyramidal tracts’
decuss = 85% fibres - medulla pyramids
(junction of medulla and sp. cord)
travel in= lateral corticospinal tract
synapse= contra. ventral horn, syn w lower motor neuron/ terminate = at level sp. cord

2nd - lower motor neuron
orig = ventral horn
term= (appendicular) mus

15%
cont. travel ipsi= 15% continue as anterior corticospinal tract
decussate = anterior white commisure (at level sp. cord)
synapse = contra. ventral horn (at spinal level)
terminate = lower motor neurons (axial mus)
*trunk mus
*posture mus
*subconcious controlled mus

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11
Q

HEAD - spinal trigeminal tracts / trigemino-thalamic system

Sensory

  1. spinal trigeminal pathway
  2. chief sensory trigeminal pathway
  3. mesencephalic
information for ..
pathway...
1st 
-touch, pressure, prop (chief sensory)
origin = 
enter = 
synapse/term =
decuss = mid pons
vs 
- pain and temp (spinal trigeminal)
origin =
enter = 
travel= 
synapse = 
*for chief some stay ipsilateral for propriocetion
- mesencephalic (reflex proprioception)
2nd
orig=
decuss = 
ascd = 
synapse and terminate =

3rd
orig =
term =

A

spinaltrigeminal tract
Sensory
- pain and temp (HEAD) = spinal trigeminal nucleus
- touch, press, proprio (HEAD) = chief sensory nucleus
- reflex proprioception (HEAD) = mesecephalic

1st 
-touch, pressure, prop (chief sensory)
origin = trigeminal ganglion
enter = mid pons (level)
synapse/term =
- ipsi. mid pons > chief sensory nucleus 
decuss = mid pons
vs 
- pain and temp (spinal trigeminal)
origin = trigeminal ganlion
enter = mid pons
travel= desc to caudal medulla
synapse = ipsi. caudal medulla > spinal trigeminal nucleus 
  • for chief some stay ipsilateral for propriocetion
  • mesencephalic (reflex proprioception)
2nd
origin= caudal med (spinal tri nucl) or pons (chief sens nu)
decuss = caudal medulla or pons
ascd = trigeminal lemniscus
synapse and terminate = thalamus (VPM)

3rd
orig = thalamus VPM
term = ipislateral cortical areas (SI and SII)

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12
Q

mechanoreceptors *4

A
  1. meissner (corpuscles) = motion detection/grip control
  2. merkel (cells) = shape/texture
  3. ruffini (corpuscles) = tangential force, hand shape, motion detection
  4. pacinian (corpuscles) = distant events thu vibration
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13
Q

Sensory for the HEAD comes mainly from… nerves

but also from…nerves

A

mainly - cn 5 (trigeminal)

but also

  • cn 7 facial
  • cn 9 glossopharangeal
  • cn 10 vagus
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14
Q

HEAD - corticobulbar pathway
(not tract more just fibres - bulbar means brainstem)

Motor
pathway..

A

corticobulbar
- motor (HEAD)

1st
origin = primary motor cortex (precentral gyrus)
travel =
-internal capsule
- cerebral peduncles (wh become) corticobulbar fibres
- leave the tract

synapse = cranial nerve nuclei (equiv to ventral horn neurons)

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15
Q

HEAD - corticobulbar pathway
(not tract more just fibres - bulbar means brainstem)

Motor
pathway..

A

corticobulbar
- Motor pathway (spinal 5)

1st
origin = primary motor cortex (precentral gyrus)
travel =
-internal capsule
- cerebral peduncles (wh become) corticobulbar fibres
- leave the tract

synapse = cranial nerve nuclei (equiv to ventral horn neurons)

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16
Q

A patient has impaired sensation of pressure and vibration in his left leg. Which of the following structures is most likely damaged?

A

Left fasciculus gracilis

17
Q

Which of the following statements best describes the anterolateral pathway?

A

2nd order neurons decussate in the spinal cord 2 levels above or below the level it enters

18
Q

Which of the following is a possible consequence of a lesion involving the left spinothalamic tract?

A

Contralateral loss of pain sensation