Neuro Flashcards
What is the most posterior part of the corpus callosum called?
Splenium
What is the main mid portion of the corpus callosum called?
Body
What is the anterior portion of the corpus callosum called?
Genu
What is the most inferior part of the corpus callosum called?
Rostrum
What are the functions of the cerebellum?
1) Maintaenance of balance and posture
2) Coordination of voluntary movements
3) Motor learning
4) Some cognitive functions
What are the lobes of the cerebellum?
1) Anterior lobe
2) Posterior lobe
3) Flocculonodular lobe
What divides the anterior and posterior lobes of the cerebellum?
Primary fissure
What divides the Floculonodular lobe from the posterior lobe?
Posterolateral fissure
What is the largest of the deep nuclei in the cerebellum?
Dentate nucleus
What is the most medial of the deep cerebellar nuclei?
Fastigial nucleus
What nuclei is situated just lateral to the fastigial nucleus?
Interposed nuclei
What nuclei is considered functionally analogous to the cerebellar nuclei but is not situated in the cerebellum?
Vestibular nuclei
What passes through the inferior cerebellar peduncle?
Primary afferent fibers from the medulla as well as efferents from the vestibular nuclei
What passes through the middle cerebellar peduncle?
Afferents from the pontine nuclei
What passes through the superior cerebellar peduncle?
Efferent fibres from the cerebellar nuclei and efferents from the spinocerebellar tract
What is the vestibulocerebellum?
It comprises of the flocculonodular lobe and connects with the lateral vestibular nuclei
What is the spinocerebellum?
Comprises of the vermis and intermediate zones as well as the fastigial and interposed nuclei
What is the cerebrocerebellum?
Comprises of the lateral hemispheres and the dendate nucleus
What do the granule cells receive input from?
Mossy fibers
What doe the granule cells project to?
Purkinje cells
Where do the mossy fibres originate?
Pontine nuclei, spinal cord, reticular formation and the vestibular nuclei
Each mossy fibre innervates one granule cell. True or false?
False - they innervate hundreds
What fibres do the granule cells form?
Parallel fibres
Where do climbing fibres originate?
Inferior olive
What do the mossy fibres project onto?
1) Granule cells
2) Cerebellar nuclei
What do the climbing fibres project to?
1) Cerebellar nuclei
2) Purkinje cells
Each purkinje fibre receives a single input form a single climbing fibre. True or false?
True - it is a single, very powerful input
What can happen if the cerebellum is damaged?
1) Deposition of movement
2) Intention tremor
3) Deficits in motor learning
What is the role of the mossy fibers?
Convey sensory information which is used to evaluate the sensory context of the movement
What is the role of the climbing fibres?
Convey error signals - thus they play a role in motor learning, making corrections
Where is CSF reabsorbed?
Superior sagittal sinus
Where are the venous sinuses located?
Between the meningeal and endosteal dural layers
Does the cavernous sinus receive blood from the orbit?
Yes
Where does the straight sinus receive blood from?
Inferior sagittal sinus and great cerebral vein
What vein do the dural venous sinuses drain into?
Internal jugular vein
Where does the majority of the blood supply to the brain come from?
Internal carotids
The left anterior cerebral artery carries blood to the motor cortex of the left leg. True or false?
False - it carries blood to the motor cortex of the right leg, the motor cortex controls the contralateral side of the body
What arteries carry blood to the basal ganglia?
Lenticulo-striate arteries
What is the cerebellum’s arterial blood supply?
1) Superior cerebellar artery
2) Anterior inferior cerebellar artery
3) Posterior inferior cerebellar artery
The middle cerebral artery is a direct continuation of the internal carotid artery. True or false?
True
The circle of willis is an uncommon site for berry aneurysms. True or false?
False - it is common
The communicating arteries in the Circle of Willis are functional anastomes between the right and left circulations. True or false?
False - Anterior is a physical link but not functional, posterior is to same side
In what lobe is Broca’s area located?
Frontal
In what area is Wernicke’s area located?
Temporal
A stroke to the temporal lobe will affect memory problems. True of false?
True
A stroke affecting the occipital lobe will result in?
Contralateral homonymous hemianopia
A stroke affecting the internal capsule is usually embolic. True or false?
False - they are haemorrhagic of the lenticostriate artery
A stroke affecting one side of the motor or somatosensory cortex would result in contralateral deficit. True or false?
True - sensory and motor control is carried out by the contralateral side of the brain
A right hemisphere stroke is likely to cause dyshasia in a left-handed individual. True or false?
False - majority of left-handed individuals are left-sided dominant as well so speech and language would be controlled on the left side
What gyrus does the primary motor cortex occupy?
Pre-central gyrus
The primary motor cortex is supplied by the middle cerebral artery only. True or false?
False - it is supplied by the ACA as well
The largest muscles of the body are given the largest area of the motor cortex. True or false?
False - the area of the motor cortex given to parts of the body depends on how richly innervated the area is
What is the Brodman’s area for the primary motor cortex is what?
4
Muscles of the lower limbs are represented medially in the motor cortex and upper limbs laterally. True or false?
True - the top medial part of the motor homolucus is the bottom of the body, moving medially and inferiorly it innervates higher up the body
Where does the corticospinal tract originate from?
The motor cortex
The corticospinal tract passes between the basal ganglia and the thalamus to enter the cerebral peduncle. True or false?
True - it passes in the internal capsule
The lateral corticospinal tract decussates at the pons. True or false?
False - it decussates at the medulla
What would happen if there was a lesion above the medullary pyramids?
There would be contralateral deficit
A stroke of the motor cortex will have a greater neurological deficit than the same size stroke of the internal capsule. True or false?
False - it would be lesser
In Parkinson’s disease there is an abnormal rhythmical output of the motor cortex. True or false?
False - the abnormal rhythmical output is from the basal ganglia
Upper motor neurones innervate the muscles directly. True or false?
False - they are innervated by the lower motor neurones
The axons of the upper motor neurones are located in the lateral white matter of the spinal cord. True or false?
True
The cell bodies of the lower motor neurones are located in the lateral horn of the spinal cord. True or false?
False - they are located in the ventral horn as the UMN cross lateral to ventral at the appropriate spinal level
A motor unit is defined as a particular muscle and all the motor neurones that innervate it. True or false?
False - a motor unit is a motor neurone and all the muscle fibres it innervates
Lower motor neurones leave the spinal cord posteriorly. Ture or false?
False - they leave ventrally (Anteriorly)
The lateral corticospnal tract is entirely uncrossed. True or false?
False - It decussates at the medullary pyramids. The anterior CST is uncrossed
What tract carries fibres to the muscles involved in balance and posture?
Vestibulospinal
What is the function of the corticospinal tract?
Controls muscles of fine movement
The anterior corticospinal tract mainly supplies the side contralateral to the originating brain hemisphere. True or false?
True
The anterior corticospina; tract is located antero-lateral to the anterior horn of the grey matter. True or false?
False - it is located medially
The lateral corticospinal tract contains less fibres than the anterior corticospinal tract. True or false?
False - Lateral = 85%, anterior = 15%
What is the function of the tectospinal tract?
Turning of the head in response to visual stimulus
What is the origin of the tectospinal tract?
Superior colliculus
What is the function of the vestibulospinal tract?
It is involved in maintaining balance and posture
Does the vestibulospinal tract cross?
No
Where does the reticulospinal tract originate?
Pons and medulla
What is the function of the reticulospinal tract?
Facilitates or inhibits the activity of descending tracts
Waht si the function of the rubrospinal tract?
Believed to be fine control of movements of the hand
Does the rubrospinal tract cross?
Yes
Is the rubrospinal tract more or less skilled than the lateral corticospinal tract?
Less skilled
Where does the rubrospinal tract originate?
Red nucleus
The reticulospinal tract provides a pathway for the hypothalamus to control the autonomic spinal outflow. True or false?
True
What type of fibre are muscle spindles formed of?
Intrafusal
What type of muscle fibre is normal skeletal muscle composed of?
Extrafusal
The middle third of the muscle spindle is associated with type 1a efferent sensory nerves. True or false?
False - afferent
The two ends of the muscle spindle are contractile. True or false?
True
What type of motor neurones innervate the muscle fibres of the muscle spindle?
Gamma motor neurones
What type of motor neurones innervate the skeletal muscle fibres?
Alpha motor neurones
Gamma motor neurones innervate extrafusal fibres. True or false?
False - they innervate intrafusal fibres, the fibres of the muscle spindle
Muscles spindles can detect both contraction and relaxation. True or false?
True
Muscle spindle activity contributes to the change in muscle resistance to stretch following a stroke. True or false?
True
The startle reflex is an example of the stretch reflex. True or false?
False
The patellar, jaw, bicep and ankle reflexes are an example of what type of reflex?
Stretch
Muscle spindles detect a change in muscle tension. True or false?
False - They detect change in length
Muscles spindles are involved in both conscious and reflex proprioception. True or false?
True
Where are golgi tendon organs located?
Junction of skeletal muscle and tendon
What are the afferent nerve fibres from the golgi tendon organ?
Type 1b to anterior horn
The golgi tendon organ’s measure the force developed by a muscle and any resultant change in length. True or false?
False - they detect the force but not the change in length
Afferent impulses of the golgi tendon organ inhibits alpha motor neurones of the muscle in which the golgi tendon organ was activated in. True or false?
True - it works to regulate the muscle tension and keep it within a normal range
The golgi tendon organ’s are only inhibitors of skeletal alpha motor neurones. True or false?
False - they excite alpha motor neurones too
Golgi tendon organ output is proportional to the muscle tension. True or false?
True
Are the golgi tendon organs involved in the clasp knife reflex?
Yes
The golgi tendon organ’s contain muscle fibres to alter tension. True or false?
False - they only meausre
Golgi tendon organ’s possess faster afferent fibres than muscle spindles. True or false?
False - they are slower
Golgi tendon organ activity inhibits the inhibition of the antagonist muscles to which the one they were activated in. True or false?
False - they inhibit the same muscle (agonist)
The receptive fields in areas like the fingers are small. True or false?
True