Neuro 1 pt6 Flashcards
Diff btwn stroke and syncope – they fall down and
blood makes it to the brain with syncope.
Who most often gets Syncope?
Young people and old people
D/O of movement and posture resultant from insult to immature CNS (in utero)
Developmental delay: failure of child to reach normal milestones of gross or fine motor, language, social-adaptive skills
Cerebral Palsy
ratio of Cerebral Palsy cases with seizures, mental retardation
1/3 have seizures
60% mentally retarded
What does TIA stand for?
Transient ischemic attack/stroke
80-85% of strokes are ___, the rest are ___
most are ischemic
rest are hemorrhagic
After a stroke, there is a 10.5% risk of another stroke in following __, but the highest risk in first __!
3 months
2 days
ischemia from TIA is reversible for how long?
<24 hours
2 causes of a stroke
blockage or hemorrhage
__% cardiac output used by brain
Brain has only _ mins of glucose energy stores; - seconds of O2 stores
20%
2 minutes glucose energy
8-10 seconds of O2 in storage
Stroke- pathogenesis can come from: (3)
ABC’s
Artery, blood, cardiac reasons
Stroke pathogenesis from ABC
Artery (4)
hemodynamic signif stenosis(low flow), atherosclerosis in neck
Carotid dissection (tear of intima of vessel)
Intracranial stenosis
Stroke pathogenesis from ABC
Blood (2)
acquired and genetic prothrombotic states.
Any inflammatory state (like UTI/PNA) will produce cytokines and interleukins which will make the platelets more “sticky”
Blood reasons for a stroke: What is an lg. protein that participates directly to plt adhesion at site of vessel injury
Von Willebrand factor
5 cardiac reasons for a stroke (hint: 3 are the same thing)
a.fib
a.fib
a.fib
PFO (patent foramen ovale)
low EF%