Neuro 01 Flashcards
What is the reticular Theory
Axons and dendrites fuse to from a large plexus that occupies all of the gray matter
Santiago Ramon y Cajal
founder of Neuroscience, coined Neuron doctrine
How was the dispute between both Theories solved
Electron microscopy showed, that pre- and postsynaptic elements are divided by synaptic cleft.
Neuronal cell types
Projection Neurons, Intrinsic Neurons
Projection Neurons
Send axons out of the structure they are located in
Intrinsic Neurons
only make synapses in their own structure
What is the spine problem
Why do excitatory axons connected to spines and not the dendritic shaft
What are ideas for the spine Problem
- serve to enhance synaptic connectivity
- are electrical compartements that modify potentials
- are biochemical compartements that implement input specific plasticity
Sir Charles Sherrington
Discovered the synapse, postulated the concept of inhibition, Reziprocal innervation
Reziprocal innervation
Activation of one muscle inhibits another one
Receptive field
The concept of the receptive field lead to the idea, that the Neuron is the anatomical, functional and perceptual unit of the brain
Problem of the Neuron doctrine
Too limiting, since ensembles of Neurons, rahter than individual cells form physiological units