Neural Regulation Flashcards
what are the changes in diameter of BVs to maintain a constant blood flow called
autoregulation
what is the Monroe-Kellie hypothesis
if one thing in the skull expands the other two must compensate
what are 3 things that inferfere with blood flow
stroke
hemorrhage
aneurysm
what is the amount of blood flow from systemic circulation required to provide adequate O2 & glucose to the brain
cerebral perfusion pressure
how is the CPP calculated
MAP-ICP
what is the normal CPP
70-100
what CPP level may cause ischemic damage
<70
which CPP value indicates irreversible damage
<50
what are some early signs of ⬆️ ICP
change in LOC
pupil changes
wekness in one extremity/side
constant headache
what are some late symptoms of ⬆️ ICP
cushing’s triad
projectile vomiting
what are the 3 components of cushing’s triad
bradycardia
bradypnea
hypertension
what causes decerebrate posturing
damage to upper brainstem
what causes decorticate posturing
damage to one or both spinal tracts
what is different between decerebrate and decorticate posturing
decorticate has hands on chest
what are 4 potential complications of ⬆️ ICP
infection
SIADH
brainstem herniation
diabetes insipidus
which 2 drugs are anti-inflammatories used to tx cerebral edema, MS
solumedrol & dexamethasone
which drug is a long acting glucocorticoid
dexamothasone