Neural control Flashcards
major components of Neural system
central nervous system (CNS)
brain (integrative control centres) and spinal cord
-cerebellum is the motor control centre
analyze and organize information
motor system planning and commands
major components of Neural system
peripheral nervous system (PNS)
outputs CNS commands and sends sensory information to CNS
primarily motto movements (movement and motor control)
afferent neurons
-relay sensory information from peripheral to the CNS (brain) along posterior column
efferent neurons
-relay information from the CNS (brain) to the peripheral or away from the brain along the pyramidal tract
-somatic nerves
-autonomic nerves
20:1 ratio afferent to efferent nerves
efferent neurons
two types
somatic neurons
motor neurons
-make up somatic nervous system
-innervate skeletal muscle
efferent neurons
two types
autonomic neurons
visceral or involuntary neurons
-make up autonomic nervous system
-activate smooth muscle, cardiac muscle, sweat and salivary glands, and some endocrine glands
sympathetic (fight or flight) and parasympathetic
which brain region is associated with processing of sensory signals?
parietal lobe
which part of the brain is primary motor cortex
pre-central gyrus
which part of the brain connects each hemisphere via commissural fibres ?
corpus callosum
which part of the brain is known as the motor control centre?
cerebellum
the ____ roots of the spinal cord contain _______ neurons, and relay information back to the CNS
dorsal
afferent
control of movement: voluntary
-require integration at the cerebral cortex
-learned movements may become “reflexive” (for example walking)
-muscle memory
ex. throwing a javelin
control of movement: reflexive
-sensor input (vision, vestibular, muscle)
-can be modulated by higher brain centres
-involved in posture
ex. regaining your balance after tripping
control of movement: rhythmic movements
-voluntary and reflexive
-initiated by cerebral cortex
-can be sustained without input from the brain
ex. running
previous research for paralysis
-focused on stem research to repair damage in individuals with spinal cord damage
new research on paralysis
-we know voluntary and rhythmic movements such as walking can actually become reflexive (not requiring input from the brain)
-if stimulus is provided below the level of the injury we may be able to obtain a state of walking
central pattern generator (CPG)
the CPG is a neural network in the lower part of the spinal cord that is thought to control locomotion
it does not require input from higher brain centres or reflexes , but the CPG output can be modified by input from the brain or reflexes
reflex arc (order)
-basic mechanism to process “autonomic muscle action-involuntary
-peripheral stimulus causes afferent neuron impulses to enter spinal cord
-transmit sensory input from peripheral receptors
-afferent neurons interconnect (synapse) with interneurons in the spinal cord to relay info to CNS
-Efferent signals return via anterior motor neuron to the muscles
-muscle responses
the central pattern generator can control walking without input form the brain or reflexes…
however the activity of the central pattern generator can be modified by input from senses, reflexes and the brain
touching a hot iron
reflex
pain receptors in the fingers transmit sensory info to spinal cord (via afferent neurons)
Efferent neurons activate the appropriate muscular response reflex action and muscular response occurs can reach the brain and tell the body to feel pain
motor unit represents an
alpha-motor neuron and the fibers it innervates
motor neurons pool represents a
Collection of alpha-motor neurons that innervate one muscle
nerve supply to muscle
single nerve or motor neuron supplies multiple individual muscle fibres (each muscles function)
-the number of muscle fibers per motor neuron (motor unit size ) is related to a muscles function
-simple movements
-complex movements
small motor unit
-only have a few fibres/motor neuron (those involved in fine movements like finger actions, eye action)
-complex precise movement
large motor unit
-may have hundreds of muscle fibers/motor neuron (those involved in gross movements like walking)
-simple movement
all muscle fibers within a given motor unit are the same __________
Type (I, IIa,IIx)
if a motor unit is activated (by higher brain centres) __________ in that unit contract
all the muscle fibers
motor neurons may receive input from other neurons originating higher up in the ________
central nervous system (closer to the brain) or the brain itself (motor cortex)
they may also receive input form reflexes, originating in the limbs (periphery)
dendrites
recipes impulses and direct toward cell body
cell body
control center
axon
delivers impulse to body
Schwann cell
covers bare axon
myelin sheath
electrical insulator of the axon
neurilemma
membrane covering the myelin sheath
nodes of ranvier
permit depolarization of axon
action potential is ______ along the axon of the motor neuron
propagated
axon is covered by
myelin (lipid sheath)
at certain points along the axon, there is a space in the myelin _____________
nodes of ranvier
nodes of ranvier allow
reinforcement of the current strength, but the current flows slower in these sections
without myelin, current leaks out and the action potential becomes weaker
nerve fiber conduction speed ______ in direct proportion to fibers __________
increases
diameter. and myelin thickness
the more myelin or thicker the axon the faster the conduction velocity of the axon
____ motor neurons have thicker axons
fast
neuromuscular junction-NMJ (motor endplate)
interface/junction between the ______
end of a motor neuron and a muscle fiber
-transmits nerve impulses to imitate muscle action
anatomical features of NMJ
-presynaptic terminals
-synaptic cleft
-postsynaptic membrane
T/F
a motor neuron pool is 1 motor neuron and many muscle fibers
false
T/F
a motor unit innervates a variety of fiber types
false
T/F
small motor units are typically involved in complex movements
true
T/F
alpha motor neurons are afferent neurons
true
at rest inside the muscle fiber (cell)
sodium is ____ on the inside as compared to the cell (ie more Na+ ________)
low
outside
at rest inside the muscle fiber (cell)
potassium is _____ on inside compared to outside the cell (ie more K+________)
high
inside
at rest inside the muscle fiber (cell)
sodium and potassium controlled by
Membrane permeability (wether or not a stimulus changes this)
at rest inside the muscle fiber (cell)
although Na+ and K+ are both positively charged there are more Na+ ions outside compared to K+ ions inside
thus the fibre cell is
more negatively charged on the inside
resting membrane potential (RMP)
-70mV
-inside negative relative to outside the membrane
relative to the RMP (-70mV)
depolarization: membrane potential becomes more _______ (>-70mV, closer to 0 or above)
positive
need to increase positive charge inside
relative to the RMP (-70mV)
repolarization: membrane potential becomes more _______ (back towards _ ___)
negative
RMP
relative to the RMP (-70mV)
hyper-polarization: membrane potential becomes more_______ than resting membrane potential (________)
negative
less than -70mV
changes in membrane polarization are ____________
signals used to receive, transmit, and integrate info within or between cells
types of signals:
endpoint signal
Depolarization OR hyper-polarization of MP, but won’t cause AP
types of signals
action potential:
substantial depolarization of MP
voltage changes
changing from -70 to -50 is
depolarization
voltage changes
changing from -70 to -90 is
hyper-polarization
voltage changes
changing from -50 to -60
repolarization
end point potential vs. action potential
wether or not it is an endpoint potential or an action potential generated in a motor neuron (thus wether the muscle reacts) depends on the of sum excitatory and inhibitory post-synaptic potentials (EPSP or IPSP)
excitatory input
known as excitatory postsynaptic potential
EPSP
inhibitory
known as inhibitory postsynaptic potential
IPSP
EPSP
depolarization of postsynaptic membrane
- facilitates (may lead to) AP
IPSP
hyper-polarizations of post synaptic membrane
- inhibits AP (are endpoint potentials)
- hyper polarizations are EPPs
facilitation
threshold/ all or none
if EPSP reaches threshold for ______ then the action potential transmits to muscle fibre
excitation
-threshold: minimum change of 15-20mV in MP depolarization ie -70mV to -50mV
action potential can be generated by
temporal summation
one or few neutrons can delivers repetitive sub threshold stimulus over a short period of time
action potentials can be generated by
spatial summation
a bunch of excitatory post synaptic potentials can be delivered from different presynaptic terminals
what is resting membrane potential
-70mV
inside of cell membrane more negative as more Na+ outside than K+ inside