Neu 11 - CSF Flashcards

1
Q

Which is the CSF circulation?

A

Lateral ventricles. Third ventricle. Cerebral aqueduct. Fourth ventricle.

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2
Q

Where is the CSF come from?

A

Choroid plexus of lateral ventricle.

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3
Q

Which structure communicates lateral ventricles and third ventricle?

A

Foramen of Monro.

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4
Q

Which structure communicates third ventricle and fourth ventricle?

A

Cerebral aqueduct (of Sylvius).

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5
Q

Which are the name of the structures that communicate fourth ventricle to subarachnoid space?

A

1)Foramina of Luschka = Lateral. 2)Foramina of Magendie = Medial.

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6
Q

Where is reabsorbed the CSF?

A

It is reabsorbed by arachnoid granulation and then drains into dural venous sinuses.

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7
Q

Which are the structures into the Carotid sheath?

A

1)Internal jugular vein. 2)Common carotid artery. 3)Vagus nerve.

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8
Q

What is the definition of a Noncommunicating hydrocephalus?

A

Caused by structural blockage of CSF circulation within ventricular system (e.g., stenosis of aqueduct of Sylvius; colloid cyst blocking foramen of Monro).

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9
Q

Which are the possibles consequences of a Noncommunicating hydrocephalus?

A

Headache, Papilledema, Uncalled herniation (eye down and out) and Death.

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10
Q

Which are the characteristics of the communicating hydrocephalus?

A

1)Poor reabsorption of CSF at the arachnoid granulations. 2)Increased Intracranial Pressure. 3)Headache. 4)Papilledema. 5)Herniation.

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11
Q

Urinary incontinence, Dementia, and ataxia are symptoms of what?

A

Triad of the Normal pressure hydrocephalus. “Wet” “wacky” and “wobbly”.

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12
Q

What is the pathology characterized by affects the elderly, CSF pressure elevated only episodically, expansion of ventricle sand distorts the fibers of the corona radiata?

A

Normal pressure hydrocephalus.

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13
Q

What is the hydrocephalus ex vacuo?

A

Atrophied brain tissue around the ventricles, and ventricles appear enlarged by comparison.

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14
Q

In which patients can we see an hydrocephalus ex vacuo?

A

Patients with Alzheimer disease, advanced HIV, pick disease. And Triad is not seen.

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15
Q

What are the characteristic features in pseudotumor cerebri?

A

1)Young, obese woman. 2)Headache -daily (worse in the morning) pulsatile, possible nausea/vomiting, possible retroocular pain worsened by eye movement. 3)Papilledema. 4)CSF pressure elevated (greater than 200 mmHg in non-obese, greater than 250mmHg in obese patient).

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16
Q

What is the most worrisome sequels of the pseudotumor cerebri?

A

It is vision loss.

17
Q

What can we see on the CT scan in a patient with pseudotumor cerebri?

A

Absence of ventricular dilation, no tumor or mass.

18
Q

What treatment options are available for managing pseudotumor cerebri?

A

1)Confirm absence of other pathology its CT and MRI of the head . 2)Discontinue any inciting agents(e.g., Vit. A, tetracyclines, corticosteroid withdrawal). 3)Weight loss in obese patients. 4)Acetazolamide - First line(Start 250mg qid or 500mg bid -> increase to 500mg qid to 1000mg qid). 5)Invasive treatment options: serial lumbar puncture, optic nerve sheath decompression and lumboperitoneal shunting (CSF shunt).

19
Q

What does CFS means?

A

CerebroSpinal Fluid

20
Q

Where is CSF generated?

A

Choroid plexus

21
Q

Where is CSF reabsorbed?

A

Arachnoid granulations (superior Sagittal sinus)

22
Q

What is the difference between communicating and Noncommunicating hydrocephalus?

A

Communicating hydrocephalus: Decreased absorption of CSF. Noncommunicating hydrocephalus: Physical obstruction.

23
Q

What clinical features characterized normal pressure hydrocephalus?

A

Triad: 1)Urinary incontinence. 2)Dementia. 3)Ataxia.

24
Q

What are the 3W’s of normal pressure hydrocephalus?

A

Wet, wacky, and wobbly. For urinary incontinence, Dementia and ataxia.