Nervous Tissue Flashcards

1
Q

What is the CNS composed of

A

spinal cord and brain

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2
Q

What is the PNS composed of?

A

cranial nerves and spinal nerves

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3
Q

What is the function of nervous tissues

A

carrying information through electrical impluses throughout the body

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4
Q

What does the somatic nervous system regulate?

A

Somatic nervous system regulates control over skeletal muscle

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5
Q

What does the autonomic nervous system regulate?

A

Autonomic nervous system regulates control over heartrate, breathing, things that are automatic

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6
Q

What are the divisions of the ANS and what do they regulate?

A

The sympathetic division of the ANS is the branch that responds when the body needs sudden or immediate action. Fight or flight response. Increase rate of function in times of need

The parasympathetic division of the ANS regulates less urgent actions. Such as digestion, waste disposal, production of bodily fluids. Regulates basal rate

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7
Q

What are the cells of nervous tissue?

A

neurones, glial

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8
Q

What is the role of neurones?

A

to send signals around the body

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9
Q

What are glial cells and what is their role?

A

support cells and to protect and provide nutrients to neurones

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10
Q

What is the basic structure of a neurone?

A

dendrite, cell body (nucleus), axon, axon terminal (boutons)

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11
Q

What is the dendrite?

A

highly branched cellular process which extends from a large cell body
they form synapses with adjacent neurones

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12
Q

What is the axon?

A

conducts action potentials
rapidly sends signals to the axon terminals
in CNS - mylienated
in PNS - can be mylienated or non mylienated

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13
Q

What are the terminal boutons?

A

neurotransmitter are released here
form synapses with neurones
electrical signal converts to chemical signal

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14
Q

What is the fundamental property of a neurone?

A

excitability

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15
Q

Describe how messages are delivered in neurons

A

Action potential travels through the neuron, reaches the terminal boutons and chemical message is released
and then received by dendrites of the next neuron and then processed to trigger an action potential in that next neurone

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16
Q

Identify the neuroglial cells located only within the central nervous system

A

Ependymal cells, Astrocytes, Microglia, Oligdendrocytes

17
Q

Identify the neuroglia cells located only within the peripheral nervous system

A

Schwann cells, Satellite cells

18
Q

What are ependymal cells?

A

Simple ciliated cuboidal epithelium
Lines fluid-filled cavities in brain (ventricles) and spinal canal
No basement membrane

19
Q

What are astrocytes?

A

Most numerous cell within the CNS.
Mediate the exchange of metabolites between neurones and the vascular system
From blood-brain barrier and have a star-like structure

20
Q

What are microglia?

A

Microglia are derived from monocytes and microphages
In response to tissue damage, these cells will transform into phagocytic cells. They will remove invading microbes and dead cells from CNS

21
Q

What are oligdendrocytes?

A

Predominant neuroglia of white matter
Form myelin sheaths around all CNS axons
Provide structural and metabolic support

22
Q

What are Schwann cells?

A

Form myelin sheaths around PNS axons
Provide structural and metabolic support
Non-myelinated axons are enveloped in cytoplasm of Schwann cell
Myelinated axons are gradually wrapped by the Schwann cell membrane to create a myelin sheath

23
Q

What is an alternative name for nerve fibres?

A

axons

24
Q

What is each nerve fibre surrounded by in the PNS (around Schwann cells)?

A

endoneurium

25
Q

What is each fascicle surrounded by?

A

perineurium

26
Q

What are bundles of fascicles surrounded by?

A

epineurium

27
Q

What does the perikaryon refer to?

A

cell body of neuron

28
Q

By looking at the individual fibres at high magnification, you will notice that there are short intervals at which the axon is not covered by a myelin sheath. What is the name of these intervals?

A

nodes of ranvier

29
Q

What is the function of the nodes of Ranvier?

A

Allows nutrients and waste to enter and exit the neuron.
Enhances conduction speed of axons

30
Q

Local anaesthesia is widely used in dental practice. The local anaesthetic acts by binding to an internal site on the Na+ channels and blocking them. Why are the nodes of Ranvier important in this process?

A

They allow Na+ to access the sodium channels.
Na+ channels are enriched at nodes of Ranvier

31
Q

Do nerve fibres differ in calibra?

A

yes

32
Q

How can the effectiveness of local anaesthesia be affected by the presence of adipocytes?

A

The potency of an anaesthetic is associated with its lipid solubility. Greater lipid solubility enhances diffusion through nerve sheaths, as well as the neural membranes of individual axons comprising a nerve trunk.

33
Q

The local anaesthetic bupivacaine is more lipid soluble compared with lidocaine. Which of these anaesthetics is most likely to be prepared at a higher dose to achieve equivalency of action with the other?

A

lidocaine

34
Q

What organs do the motor neurones at the lumbar level predominantly innervate?

A

lower limb muscles

35
Q

What organs do the motor neurones at the cervical level predominantly innervate?

A

upper limb muscles

36
Q

In which direction does information typically travel in the ventral horns?

A

downwards

37
Q

In which direction does information typically travel in the dorsal horns?

A

upwards

38
Q

Where are Purkinje nerve cells found?

A

cerebellum