Epithelial Tissue Flashcards

1
Q

What is the primary function of epithelia?

A

Act as a barrier and lines all body surfaces and tissues

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2
Q

What are the additional functions of epithelia and where are they found?

A

Protection from mechanical abrasion found in skin and oral cavity

Diffusion of gases, nutrients and waste between blood and surrounding tissues found in lungs and blood capillaries

Absorption of nutrients in the gastrointestinal tract/renal tubules

Secretion of sweat, mucus, enzymes, hormones in glands and ducts

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3
Q

How are epithelial cells arranged?

A

Continuous sheets of tightly bound cells. Epithelial cells are polarised. Apical surface is the top of cell, facing the external surface. Basal surface is bottom of cell, facing the internal surface. No passage through epithelia as cells are bound together.

Sit on top of basement membrane usually over a vascular connective tissue

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4
Q

What are desmosomes?

A

Desmosomes are strong junctions that anchor adjacent cells together, they ensure epithelial tissues can stretch and maintain contact

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5
Q

What does a tight junction do?

A

Tight junctions at the lateral sides of the cells can create an impermeable layer. Prevents water passage

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6
Q

How can epithelial structure differ?

A

Shape, Number of layers, Apical specialisations

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7
Q

Describe the three shapes

A

Squamous - appear flat and wide

Cuboidal - appear square with similar height and width

Columnar - taller than wider

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8
Q

What is the difference between desmosomes and hemidesmosomes

A

Desmosomes - they hold together adjacent cells
Hemidesmosomes - they hold cells to the basement membrane

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9
Q

What is simple epithelia?

A

Simple epithelia consists of a single layer of cells

They are almost always found at interfaces involving select diffusion, absorption and/or secretion

Provide little protection against mechanical abrasion so are not found at surfaces subjected to stress

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10
Q

What is stratified epithelia?

A

Epithelium consisting of two or more layers of cells

Have a protective function

Degree of stratification related to kinds of physical stresses to which the surface is exposed

Poorly suited for absorption and secretion as they are thick

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11
Q

What is pseudostratified?

A

Single layer of cells that appear stratified
Nuclei at different heights and not all cells reach apical surface

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12
Q

What is transitional stratified and where is it found?

A

Transitional stratified epithelia are where the cells are not uniform.
They support organs where organs where stretch and recoil is important such as the bladder

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13
Q

Where is a simple columnar ciliated found?

A

female reproductive tract (cilia transport ovum from ovary to uterus

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14
Q

Where is a pseudo stratified columnar ciliated found?

A

respiratory tract

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15
Q

What are the apical specialisations and where are they found?

A

Microvillifound in small intestines for absorption, it increases apical surface area

Ciliafound in respiratory tract, move mucus and matter for movement (motility)

Keratin isa strong protein with rough layer for protection. found in skin, hair and nails

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16
Q

What are goblet cells, where are they found and what do they do?

A

Goblet cells are modified columnar epithelial cells and scattered throughout simple columnar epitheliums of the respiratory and gastrointestinal systems. They synthesise and secrete mucus.

17
Q

What is the most common type of stratified cells and where is it found?

A

stratified squamous cells and in skin and the oral cavity

18
Q

Describe the process of stratified squamous cells in skin

A

Cells mature from basal layerfrom continuously dividing stem cells thengradually migrate to surface and are shed asanucleatesquames.

19
Q

What appearance do microvilli create?

A

brush border

20
Q

What appearance do cilia create?

A

longer and thicker than microvilli. hair-like

21
Q

How does ulceration happen?

A

a break in the continuity of the epithelium

22
Q

What type of epithelium is the convoluted tubules?

A

simple cubodial epithelium