Muscle Tissue Flashcards

1
Q

What are muscles specialised for?

A

contraction

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2
Q

What are the types of muscle tissue and what is their role?

A

skeletal - movement of body
cardiac - movement of blood
smooth - movement of gases, fluids and solid through visceral organs

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3
Q

How is skeletal muscle classified?

A

somatic (voluntary) & striated

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4
Q

How is cardiac muscle classified?

A

autonomic (involuntary) & striated

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5
Q

How is smooth muscle classified?

A

autonomic (involuntary) & non striated

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6
Q

What is a striated appearance?

A

banded

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7
Q

What is the name of the outer connective tissue that encases entire muscles?

A

epimysium

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8
Q

What is the name given to the connective tissue layer that surrounds bundles of muscle fibres, known as fascicles?

A

perimysium

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9
Q

What is the name given to the connective tissue layer that surrounds individual skeletal muscle fibres?

A

endomysium

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10
Q

What name is given to the structure formed by the coming together of the 3 connective tissue layers in skeletal muscle, at the tapering ends?

A

tendon

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11
Q

What is each skeletal cell packed full of?

A

myofibrils which create the striated appearance

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12
Q

What are myofibrils made from?

A

repeating proteins units called myofilaments made from actin and myosin

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13
Q

What are the dark bands in electron-microscopy?

A

myosin

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14
Q

What are the light bands in electron-microscopy?

A

actin

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15
Q

What are the contractual units called?

A

sarcomeres

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16
Q

How do they contractual units contract?

A

actin and myosin slide over each other, overlapping due to a conformational change in the sarcomere

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17
Q

Describe which organelles are specialized for skeletal muscle

A

plasma membrane called sacrolemma
cytoplasm called the sacroplasm
sarcoplasmic reticulum
multinucleated

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18
Q

What a motor unit?

A

A single motor neurone together with all the muscle fibres it innervates

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19
Q

What is the process of muscle contraction called?

A

Excitation-Contraction coupling

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20
Q

What is the chemical messenger converted from neuronal action potential that simulates the action potential in skeletal muscle cells?

A

acetylcholine

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21
Q

What structural feature of skeletal muscle fibres propagates action potentials into the interior of the cell?

A

T tubules

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22
Q

What happens at the action potential?

A

When the muscle is stimulated, calcium ions are released from its store inside the sarcoplasmic reticulum, into the sarcoplasm (muscle )

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23
Q

What structural feature of skeletal muscle fibres sequesters calcium away from myofibrils during relaxation?

A

sarcoplasmic reticulum

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24
Q

What is the function of cardiac muscle?

A

Specialized for continuous autonomous contractions
Pump blood through the cardiovascular system

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25
What is the structure of cardiac muscle?
elongated, branched cylindrical cells 1 or 2 centrally located nuclei similar arrangement of contractile proteins as in skeletal muscle causing striated appearance
26
What are the layers of cardiac muscle?
Pericardium (P): Outer supporting tissue layer Myocardium (M): Cardiac muscle tissue Endocardium (E): Single layer of endothelial cells
27
What do the intercalated discs at the end of cardiomyocytes contain?
desmosomes, gap junction
28
What are the cells of cardiac muscle?
cardiomyocytes
29
What are the similarities between cardiac and skeletal muscle?
identical arrangement of sacromeres both have t tubules and sarcoplasmic reticulum contraction happens by sliding -filament mechanism
30
What are the differences between cardiac and skeletal muscle?
In cardiac muscle cells the SR slowly leaks Ca so that the heart can generate its own action potential instead of only releasing at an action potential no motor neuron needed in cardiac muscles as single travels through gap junctions at the end of intercalated discs
31
All cells in cardiac muscle work as a single unit, what is this called?
syncytium
32
What is a 'conducting system'?
The conducting system is a group of cells that can initiate the contractions without any outside stimulus
33
What can undergo spontaneous depolarisation?
pacemaker cells
34
Describe the conducting system of cardiac muscle
Signal to contract will travel from sinotrial node (pacemaker cells) to atrioventricular node – this movement will trigger the atria to contract and push blood from atria to the ventricles. - from the node the signal to contract will travel to the bundle of his to the purkinje fibres where they reveal that signal to the cardiac muscle cells
35
Where is smooth muscle found?
lining hollow organs
36
What is the structure of smooth muscle?
Elongated, spindle-shaped cells with tapered ends Single centrally located nuclei No sarcomeres hence no striations
37
What is peristalsis?
Peristalsis is a wave of contraction in the gastrointestinal tract followed by relaxation
38
What only exists in smooth muscle?
desmin
39
What does the smooth muscle look like contracted?
globalar
40
What does the smooth muscle look like relaxed?
elongated
41
What does the smooth muscle not have?
no myofibrils or sarcomeres
42
What is the adventitia referred to in the abdominal cavity?
serosa
43
What name is given to the innermost layer (luminal surface) that is composed predominantly of epithelium in the intestine?
mucosa
44
Name the section directly beneath the mucosa
submucosa
45
Name the section directly beneath the submucosa
muscularis propria
46
Name the section directly beneath the muscularis propria
serosa
47
What are mucus-secreting cells called?
goblet cells
48
How many nuclei does smooth muscle have?
one
49
What is the position of the nuclei in cardiac muscle cells?
Central
50
What is the zigzag portion called that forms the boundary ends of each sarcomere?
z line
51
What are the thick filaments in sarcomeres?
myosin
52
What are the thin filaments in sarcomeres?
actin
53
What do T tubules do?
they also transmission of the action potential across the sarcoplasm
54
Where is calcium concentrated?
sarcoplasmic reticulum
55
What is the M line?
the middle of the sarcomere
56
What is the I line?
where actin filaments are (no overlapping)
57
Why are intercalated discs present in cardiac muscle?
for rapid transmission of stimuli between cells and points of anchoring
58
How are actin and myosin arranged in smooth muscle?
criss-cross lattice
59
In smooth muscle, calcium binds to what molecule to create contraction?
calmodulin
60
What is the band that contains only myosin filaments?
H band
61
What is the band where myosin and actin filaments overlap?
A band