Nervous System Flashcards

1
Q

Order of flow of info in the PNS

A

Receptors-> sensory nerves -> spinal cord/ brain -> motor nerve -> muscle/ internal organ

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2
Q

What are the 3 ways of classifying receptors

A
  1. Location (body surface/ internal organs
  2. Types of stimulus detected (pain/temp)
  3. Structure (free/encapsulated)
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3
Q

What’s motor endings

A
Axon terminals of muscle neurones 
-
Usually ACh 
-
Can be norepinephrine at visceral muscle and glands
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4
Q

What at the two components of peripheral nerves

A

Efferent neurones

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5
Q

Describe afferent neurones

A
  1. Sensory neurones
  2. Axons enter spinal cord through dorsal roots
  3. TOWARDS the CNS
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6
Q

Describe efferent neurones

A
  1. Motor neurones
  2. Leave spinal cord through ventral roots
  3. AWAY from CNS
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7
Q

How many nerves at each spinal level

A
Cervical: C1-C8
Thoracic: T1-T12
Lumbar: L1-L5
Sacral: S1-S5
Coccygeal: Co1
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8
Q

Two enlargements in spinal cord?

A

Where many nerves enter/ exit

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9
Q

Describe spinal nerves

A
  1. Contains a mix of sensory and motor
  2. Sensory enter Dorsal root
  3. Motor exit ventral root
  4. Afferent neurones in dorsal root have cell bodies in dorsal root ganglion
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10
Q

Two party’s of nervous system

A
Somatic: skin, skeletal muscle, joints.
Somatic sensory(afferent) / somatic motor(efferent)

Visceral: emotional reactions
Can be sympathetic or parasympathetic

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11
Q

Main difference in pathway of visceral and somatic

A

Visceral:

Visceral motor neurone-> down spinal cord-> preganglionic neurone -> synapse at autonomic ganglia-> ganglion of neurones

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12
Q

Define Dermatomes

A

Area of skin innverated by branches of a signal spinal nerve

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13
Q

Define myotomes

A

A group of muscles innverated by a single nerve root

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14
Q

6 steps to a sensory pathway

A
  1. Adequate stimulus
  2. Receptor
  3. Primary sensory neurone
  4. Sensory nucleus
  5. Thalamus
  6. Primary sensory cortex
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15
Q

3 things that mediate receptors

A
  1. Modality (visual, mechanical)
  2. Intensity- sensory threshold
  3. Duration - adaptation
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16
Q

Define sensory threshold

A

Smallest intensity at which a sensation is detected

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17
Q

Define adaptation

A

Intensity diminishes when stimulus is continuous for a period of time

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18
Q

Describe receptive fields

A
  1. The area that activates a receptor/ sensory neurone
  2. High receptor density means small receptive fields
  3. Overlapping receptive fields allows sensory discrimination
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19
Q

Define cortical magnification

A

Cortical maps are distorted are distorted in proportion to density of peripheral innervation/ density of receptors

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20
Q

Define lateral inhibition

A

This is done by sensory neurones having inhibitory synapses with neighbouring neurones, thus amplifying difference in activity of neurones

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21
Q

Describe the role of the thalamus in sensation

A
  • Nuclei process and modify information

- connections contain a mixture of serial and parallel processing

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22
Q

What are cortico-fugal fibres

A

These filter ascending information
-
Perception therefore differs from sensation

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23
Q

Divergence in connectivity as cortex is reached

A

Primary sensory cortex-> sensory association cortex-> polysensory association cortex

24
Q

Conscious level info travels in two main tracts:

A
  1. Dorsal (posterior) column/ medial lemniscus (touch)

2. Anterolateral system tracts (pain)

25
Where dose decussation occur in a sensory pathway
Between Nucleus (PNS) and Thalamus (CNS)
26
Names of the medial and lateral parts of the dorsal column
Medial: gracile fasiculus (lower body, T6)
27
What tract carry’s propriceprion information
Spinocerebellar (dorsal and ventral parts)
28
What tract carry’s pain and temperature
Spinothalamic tract (antherlateral)
29
Where do axons in the dorsal column make their first synapse?
Dorsal column nuclei (cuneate and gracile nucleus) in the medulla.
30
Where does the dorsal column tract go after medulla
They decussate then synapse at the thalamus (called the medial lemnicus at this point)
31
Describe the thalamus
1. Located either side of 3rd ventricle 2. Receive info via second order neurones 3. Multiple nuclei
32
Role of the thalamus?
1. Integrates, modulates and relays info | 2. Thalamus radiation projects to sensory cortex via internal capsule
33
Two thalamus nuclei
Ventral posterior medial: head/face | Ventral posterior lateral: body
34
Nerve that supply’s sensory information from the head/face
Trigeminal nerves - Also glossooharyngeal and Vagus nerves
35
Sensory pathway from head/face
Trigeminal-> second order neurone in ipsilateral trigeminal nucleus-> decussate and project via trigeminal lemmiscus to VPM nucleus of thalamus-> sensory cortex
36
3 trigeminal nuclei
Principle sensory nucleus: touch, pressure and conscious proprioception Spinal nucleus: pain and temp Mesencephalic nucleus: non- conscious proprioceptive info
37
What are pain receptors called?
Nociceptors- they are polymodal so will respond to many different stimuli
38
Two types of nociceptive fibres
1. A delta fibres (fast sharp pain) | 2. C.fibres (non-myelinated) slow, dull pain
39
3 types of pain receptor stimuli
1. Mechanical - high threshold mechanoreceptors 2. Temperature - heat gated cation channels - transient receptor potential channel receptors 3. Chemical activation - free nerve ending C fibres
40
What are the two general parts to the anterolateral system
Direct tracts - lateral ST tract: pain and temp - anterior ST tract: crude touch and pressure Indirect tracts - modulate pain - spinoreticular - spinocerebellar - slinitectal
41
Difference between pain and non-pain sensory information
- both enter the dorsal root ganglion However - first synapse for pain is in the spinal cord
42
Why is the spinal-thalamus tract called the anterolateral tract?
Because it’s in the anterior lateral section of the spinal cord
43
Where does the anterolateral tract synapse in the thalamus?
Ventral posterior nucleus
44
Name of tract between receptors and spinothalamic tract
Lissauer tract
45
Where does decussation happen as a rule of thumb
Always in the second order neurone
46
Where does first order neurone (pain) synapse in the trigeminal nucleus
Pars caudalis | Lowest part
47
Where dose crude touch synapse in the trigeminal nucleus
Spinal part of 5th nucleus
48
Where does fine touch info synapse in the trigeminal nucleus
Sensory nucleus
49
Describe afferent regulation of pain
1. Touch pathways make inhibitory interneurones at the substantia gelatinosa 2. Diminishing pain sensations in the anterolateral tract 3. Such as rubbing hand 4. Called gate-control theory of pain
50
Describe descending modulation of pain
1. Periaqueduct of midbrain 2. Raphé of reticular formation 3. Synapse in spinal cord, decreasing pain
51
How many pairs of cranial nerves?
12
52
Number and name of each nerve
1. Olfactory 2. Optic 3. Ocularmotor 4. Trochlear 5. Trigeminal 6. Abduct 7. Facial 8. Vestibulocochlear 9. Glossophaeyngeal 10. Vagus 11. Accessory 12. Hypoglossal
53
Describe olfactory nerve
1. Have endings in nasal mucosa 2. Pass through cribriform plate 3. Synapse at olfactory bulb
54
3 nerves that control eye muscles
1. Oculomotor 2. Trochlear 3. Adbucens
55
Accessory nerve controls...
Neck muscles
56
Hypoglossal nerve controls
Tongue muscles