Nervous system Flashcards
Bootcamp + booster
neuron
is the most basic unit of the nervous system.
-contains three parts: the soma, Dendrites, and the axon
Soma
Cell body
Dendrites
receive information and
transfer it to the cell body
Axon
sends signals out
Axon hillock
where the soma connects
to the axon; action potentials are generated here
Glial cells
nervous tissue support cells
that are capable of cell division
Oligodendrocytes
produce myelin sheath in the central nervous system (CNS)
Schwann cell
produce myelin sheath in the peripheral nervous system (PNS)
Mnemonic: COPS
CO: central nervous system (CNS)/Oligodendrocytes
PS: peripheral nervous system (PNS)/Schwann cell
Myelin sheath
fatty sheaths that act as insulators and are separated by Nodes of Ranvier that allow the action potential to travel continuously down the axon, jumping from node to node, a process known as saltatory conduction, that speeds up the impulse
saltatory conduction
are separated by Nodes of Ranvier that allow the action potential to travel continuously down the axon, jumping from node to node
Nodes of Ranvier
gaps between myelin sheaths where ion exchange occurs.
Microglial
- phagocytes of the CNS
- are macrophages that protect the central nervous system (CNS).
Ependymal cells
use cilia to circulate cerebrospinal fluid, which cushions the CNS
Satellite cell
groups of cell bodies in the PNS that serve as support cells
Sensory (afferent) neurons
receive stimulus from the environment and send the stimulus to the brain for processing (e.g., neurons in the retina of the eye)
- send signals to the spinal cord and subsequently the brain through dorsal roots.
Astrocytes
provide physical support to neurons of the CNS and maintain the mineral and
nutrient balance
- form the blood-brain barrier
Association (interneuron) neurons
located in the spinal cord and brain; receive impulses from sensory neurons and send impulses to motor neurons.
- 99% of nerves are interneurons
- Are found in reflex arcs but some do not require an interneuron
Motor (efferent) neurons
send signals back out to the muscles through ventral roots.
- May stimulate muscles, sweat glands, or cells in the stomach to secrete gastrin
Electrical transmission
a bidirectional action potential that travels along membranes of gap junctions; is less common in the body, fast, and found in cardiac and visceral smooth muscle
Steps of Nerve Impulse Transmission
- Resting potential
- Action potential
- Repolarization
- Hyperpolarization
- Refractory period: Absolute refractory period, and Relative refractory period
Chemical transmission
a unidirectional action potential that is most typical in animal cells
synapse
is the space between two neurons.
presynaptic
neuron sends the signal and releases neurotransmitters into the synapse
postsynaptic
neuron receives the signal by interacting with the released neurotransmitters.
Steps of Transmission Across Chemical Synapse
- Ca2+ gates open
- Synaptic vessels release
neurotransmitter - Neurotransmitter binds with
postsynaptic receptors - Postsynaptic membrane is excited or inhibited: Excitatory postsynaptic potential (EPSP) and Inhibitory postsynaptic potential (IPSP)
- Neurotransmitter is degraded/recycled/diffused away
Diameter
greater diameter allows an
impulse to propagate faster since a larger diameter results in a less resistance to the flow of ions (think of passing water
through a large pipe vs. a small one)
Myelination
heavily myelinated axons
allow impulses to propagate faster since Na+ ions can’t leak out, thereby driving saltatory conduction to occur faster
excitatory postsynaptic potential (EPSP)
(EPSP) is a graded potential that depolarizes the membrane.
In an EPSP, excitatory neurotransmitters cause Na+
ion gates to open and let Na+ ions flow into the cell.
inhibitory postsynaptic potential (IPSP)
is a graded potential that hyperpolarizes the membrane. Inhibitory neurotransmitters cause K+ ion gates to open and let K+ ions flow out of the cell. Another IPSP type allows influx of Cl- ,allowing negative Cl- ions in.
Acetylcholine (Ach)
secreted at neuromuscular junctions and cause muscle contraction or relaxation
Glutamate
neurotransmitter at the
neuromuscular junction in
invertebrates, and is the most
common CNS neurotransmitter in vertebrates
types of Amino acids neurotransmitters
Glutamate, gamma aminobutyric Acid (GABA), and Glycine
Gamma aminobutyric acid (GABA)
inhibitory neurotransmitter among brain neurons
Glycine
inhibitory neurotransmitter
among synapses of the CNS outside the brain
Amino acid derived (biogenic amines) Neurotransmitters
Epinephrine, norepinephrine,
dopamine, and serotonin (5HT) -
secreted between neurons of the CNS
- Epinephrine/norepinephrine act in the sympathetic nervous
system and are released from
post ganglionic nerves
Gases neurotransmitters
Unlike most neurotransmitters, these are not stored in vesicles and are actually synthesized and released on demand! Example: nitric oxide (NO)
Neuropeptides neurotransmitters
short chains of amino acids and are a diverse group including substance P and endorphins
central nervous system (CNS)
is composed of the brain and spinal cord.
peripheral nervous system (PNS)
is composed of nerves branching off the CNS.
what three areas can the brain divide to during embryonic development?
Forebrain, Midbrain and Hindbrain
Forebrain
largest and most
important brain region; contains the
cerebrum, which includes the
following: Cerebral Cortex, Olfactory blub, thalamus, hypothalamus, Basal ganglia, adn Hippocampus
Cerebral Cortex
processes sensory input, important for perception, memory, voluntary movement, and learning
Olfactory bulb
smell