Nephrotic syndrome Flashcards
1
Q
Nephrotic syndrome
A
proteinuria > 3 g/mol
U-protein: Creatinine ratio >/= 0.2g/mmol
hypoalbuminaemia < 25g/L
oedema
associated with hyperlipidaemia but not of diagnostic value
2
Q
Clinical features find child NS
A
periorbital oedema peripheral oedema ascites anasarca - generalised oedema hepatomegaly splenomegaly large kidneys pleural effusions pericardial effusions
3
Q
Secondary causes of nephrotic syndrome
A
post infectious glomerulonephritis chronic infections - HIV, Hepatitis B and C, CMV drugs - ACE-I and NSAIDs Auto-immune diseases - SLE HUS Toxins - mercury vasculitis - HSP
4
Q
Complications
A
infections - capsulated organisms like s pneumoniae
thrombosis
hernias
volume depletion and acute renal failure
decreased levels of carrier proteins leads to
= hypothyroidism, rickets, iron deficiency
PEM
