Nephrotic/Nephritic Buzzwords Flashcards

1
Q

Effacement of foot processes on EM in an adult

A

focal segmental glomerulosclerosis

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2
Q

Effacement of foot processes on EM in a kid

A

minimal change disease

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3
Q

Segmental sclerosis and hyalinosis on LM

A

focal segmental glomerulosclerosis

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4
Q

Spike and dome appearance with sub epithelial deposits on EM

A

membranous nephropathy

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5
Q

Diffuse capillary and GBM thickening (LM)

A

membranous nephropathy

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6
Q

Congo red stain shows apple green birefringence under polarized light

A

amyloidosis

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7
Q

Tram track appearance due to GBM splitting

A

Type 1 MPGN

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8
Q

Intramembranous IC dense deposits

A

Type 2 MPGN

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9
Q

Associated with C3 nephritic factor

A

Type 2 MPGN

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10
Q

Associated with HBV, HCV

A

Type 1 MPGN

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11
Q

Associated with HIV, sickle cell, heroin abuse

A

focal segmental glomerulosclerosis

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12
Q

Associated with Ab to phospholipase A2 receptor

A

membranous nephropathy

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13
Q

Nephrotic presentation of SLE

A

membranous nephropathy

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14
Q

Associated with Hodgkin lymphoma in a kid

A

minimal change disease

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15
Q

Associated with multiple myeloma, TB, and rheumatoid arthritis

A

amyloidosis

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16
Q

Granular with subendothelial immune complex deposition (IF)

A

type 1 MPGN

17
Q

Kimmelstiel-Wilson lesions and mesangial expansion

A

diabetic glomerulonephropathy

18
Q

lumpy bumpy (IF)

A

acute post strep GN

19
Q

Subepithelial immune complex humps (EM)

A

acute post strep GN

20
Q

Associated with increased anti-DNase B titers and decreased complement levels

A

acute post strep GN

21
Q

Proteinuria in nephrotic syndrome is >___ per day

A

3.5g

22
Q

Crescent moon shape (LM, IF)

A

rapidly progressive glomerulonephritis

23
Q

IgG, IgM, C3 deposition along GBM and mesangium

A

acute post strep GN

24
Q

Antibodies to GBM and alveolar basement membrane

A

Goodpasture syndrome

25
Q

MCC death in SLE

A

diffuse proliferative glomerulonephritis

26
Q

Capillary wire looping (LM)

A

diffuse proliferative glomerulonephritis

27
Q

Subendothelial and sometimes intramembranous IgG-based immune complexes often with C3 deposition (EM)

A

diffuse proliferative glomerulonephritis

28
Q

IgA-based IC deposits in mesangium

A

IgA nephropathy (Berger disease)

29
Q

Seen with Henoch-Schonlein purpura

A

IgA nephropathy (Berger disease)

30
Q

Thinning and splitting of GBM with deafness and sometimes eye problems

A

Alport syndrome

31
Q

c-ANCA +

A

Wegeners (granulomatosis with polyangiitis)