Nephrology/GU Flashcards
What is hematuria?
5+ RBC in urine
What dz can cause hematuria?
BAPI HUH Benign familial Alport Post strep glemerulonephritis IgA - Berger Hemolytic uremic UTI Hypercalcuria
What is benign familial hematuria?
RBC in urine
d/t family gene - autosomal dominant
Benign familial hematuria - sx?
normal:
- exam
- renal fxn
Adult smokes + painless hematuria = ?
what can this lead to?
transitional cell carcinoma
Benign familiar hematuria - PE?
prerenal: dark
renal: casts
post renal: bright red
What is Alport sx?
can lead to ESRD
autosomal recessive
What are the genetic caused hematuria dz?
benign familial hematuria
Alport sx
Hematuria + hearing loss + vision loss = ?
Alport sx
Alport sx - dx?
renal bx
What is post strep glomerulonephritis?
d/t a strep infxn: throat or skin
When does post strep glomerulonephritis occur?
1-2 days after strep infxn
Which hematuria dz can cause HTN?
post strep glomerulonephritis
IgA
HUS
How to differentiate between post strep glomerulonephritis and IgA?
get ASO titers to r/o post strep glomerulonephritis
Post strep glomerulonephritis - tx?
control HTN
supportive
fluid balance
Baby had URI 1-2 days ago + hematuria + RBC casts = ?
IgA nephropathy
Post strep glomerulonephritis - labs?
increased BUN/Cr
UA: hematuria + RBC casts
IgA nephropathy - tx?
prednisone
ACE inhibitors
Athletic child w/ fever comes in with brown urine?
myoglobinuria/rhabdomyloysis
Myoglobinuria/rhabdomylosis - UA?
NO RBC
Myoglobinuria/rhabdomylosis - tx?
mannitol to flush it all out
rehydrate
HUS - sx?
rash
dark urine
HTN
bloody diarrhea
HUS - labs?
high PTT
high BUN/Cr
RBC + casts
What dz have RBC + casts?
HUS
post strep glomerulonephritis
IgA
HUS - dx?
stool: EHEC
HUS - what to be careful of?
abx
HUS - tx?
supportive
Henoch schonlein purpura?
IgA mediated
rash waist down
arthritis
abdominal pain
Baby has abdominal pain + arthritis + rash waist down =?
henoch schonlein purpura
Henoch schonelin purpura - labs?
CBC - check for non thrombocytopenia
What is proteinuria?
child: >30-40mg/kg/day
adult: >3-3.5g
protein: Cr > 0.2
What is the gold standard to check for protein?
24 hr urine
Orthostatic proteinuria?
protein in urine when sitting/standing
Orthostatic proteinuria - dx?
morning first void > 24 hr urine
Orthostatic proteinuria - tx?
benign
Minimal change dz?
COMMON CX OF PROTEINURIA IN KIDS
Minimal change dz - prognosis?
does NOT lead to ESRD
Baby comes in with sudden onset of edema?
minimal change dz
What kidney dz can be treated w/ ACE?
IgA
minimal change dz
Minimal change dz - dx?
renal bx
Bug for UTI?
e coli
adenovirus
female comes in w/ fever but NO URI?
UTI
RF for UTI?
female
male not circumcised
constipation
UTI can lead to ESRD if?
recurrent 3x
UTI sx?
vomit diarrhea abdominal pain strong smelling urine NO CVA tenderness in kids suprapubic pain
What to look out for in babies w/ systemic sx?
pyleo
Baby <12 mo has fever w/ no source?
UA
Gold standard for clean catch in babies?
catheter b/c bag is not clean catch
Dx for UTI in babies?
clean catch UA C&S
If urine culture comes back with flora?
prob not UTI