Nephrology Flashcards
Formula for calculated ososmolality?
If pseudo hyponatremia is present the calculated osmolality will be lower than measured osmolality
2(sodium)+ glucose/18 + (BUN/2.7)
A BUN / Cr ratio greater than 20 is suggestive of
Hypovolemia
Urine osmolality can be used to distinguish between impaired water excretion, SIADH, and pathological water intake ( polydipsia) . In SIADH , the urine will be inappropriately concentrated with urine osmoles of
> 100mOsm/L/Kg
Patient is unable to retain sodium
Discontinue ACE-I if creatinine increases by more than
30%
Stage 4 chronic kidney disease is defined as an estimated GFR of?
GFR 15-30
KDOQI recommends that patients with hypertension and GFR >30 to be treated with
Thiazides
KDOQI recommends in pts with hypertension and GFR
Loop diuretics
KDOQI recommends that both dialysis and nondialysis patients with CKD receiving erythropoietin stimulating agents (ESA) therapy - Hb target should be
11-12
Hb should be monitored monthly
PH
Metabolic acidosis
CKD-MBD characterized by secondary hyperparathyroidism is caused by
Phosphate retention
Decreased free Ca
Decreased 1,25 - dihydroxyvitamin D
Measure serum Ca, PO4, and intact PTH in all patients with a GFR
Definition of hyponatremia is a plasma sodium concentration below
135