Arthriditides Flashcards

1
Q

How many points required to diagnose rheumatoid arthritis

A

6 points totaled or greater

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2
Q

In treating rheumatoid arthritis, when should DMARDS be started

A

As early as possible to delay disease progression

Use NSAIDS at at the lowest dose for relief

Steroids plus MTX not bio logics

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3
Q

Dactylitis is associated with which arthritide

A

Psoriatic arthritis
Nail changes common

Plaques in scalp

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4
Q

Diagnosis psoriatic arthritis

A

Predominant joint DIP
Lacks RF factor no nodules

Total 3 points

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5
Q

Treatment psoriatic arthritis

A

MTX

Sulfasalazine

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6
Q

What is osteoarthritis

A

Chronic joint disorder in which there is a progressive softening and disintegration of articular cartilage accompanied by new growth of cartilage and bone at the joint margins osteophytes and capsular fibrosis

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7
Q

X-ray changes of osteoarthritis

A

Subchondral sclerosis

Joint space narrowing

Osteophytes

Cysts

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8
Q

Nonsurgical treatment osteoarthritis

A

ACETOMINAPHEN

Topical NSAIDS
Weight loss

Physiotherapy

Walking aids

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9
Q

What is the Definition of gout

A

Deposition of monosodium urate crystals in tissues

Typically first MTP joint, ankle, mid foot, knee

May mimic infection

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10
Q

Treatment gout 4 stages

A

Asymptomatic hyperuricemia - don’t treat

Acute flares- colchicine, NSAIDs ( low dose NSAIDs indomethacin or naproxen

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11
Q

Finding specifically diagnostic of classic rheumatoid arthritis

A

Rheumatoid joint erosions

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12
Q

Anticentromere assoc with

A

Scleroderma

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13
Q

Indications for arthrocentesis

A

Suspicion infection

Suspicion crystal induced arthritis

Suspicion hemarthrosis

Differentiating inflammatory from noninflammatory arthritis

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14
Q

What meds increase serum colchicine

A

Statins, digoxin, macrolides, Azores, CCBs, grapefruit

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15
Q

Colchicine loading dose

A

1.2 mg then 0.6 mg 1 hour later

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16
Q

In treating gout target serum urate level is

A
17
Q

What are the 3 uricosuric agents?

Which is FDA approved

A

Probenecid- only FDA approved agent
Losartan
Fenofibrate

18
Q

Blocks the conversion of hypoxanthine to Uric acid

A

Xanthine oxidase inhibitors

Allopurinol
Oxypurinol
Febuxostat

19
Q

Ankylosing spondylitis

A
Mainly affects spine and SI joints
Male>female
HLA B27 in 90% 
Synovitis 
Morning stiffness in back
20
Q

Most common cause septic arthritis

A

Gonoccocal
5-7 days h/or fever, chills, lesions
MONOARTHRITIS

21
Q

Lyme arthritis

A

Erythema migrans 7-10 days after borellia bergdorferi tick bite