Nephro, GI Flashcards
Autosomal recessive metabolic disorder of lysine, hydroxylysine, and tryptophan metabolism
Glutaric Aciduria Type I (GA-I)
Renal Threshold: plasma glucose
200mg/dl
one nephron is already saturated
Renal Transport Maximum: plasma glucose
375mg/dL
all nephrons are already saturated)
Clearance equal to GFR
inulin, creatinine
filtered but not secreted not absorbed
marker for kidney function
Only solute not mainly reabsorb in the PCT
magnesium reabsorb in the TAL of LH
25% PCT
Creates “graded osmolarity” in renal medulla
LOH
Preserves “graded osmolarity” in renal medulla
Vasa recta
layer of GIT responsible for GI secretions
Muscularis mucosae
innervated by Meissner plexus
layer of GIT responsible for motility
Circular and and longitudinal muscle
innervated by Auerbach plexus
Myenteric is mainly excitatory except
pyloric sphincter, ileocecal valve
Contractile tissue in the GI is made up of UNITARY SMOOTH MUSCLE, except
Pharynx
Upper 1/3 esophagus
External Anal Sphincter
Most common stimulus for GI peristalsis
Distention
Gastrocolic reflex is mediate dby
Parasymphathetic NS
CCK
Gastrin
normal BM in newborn
site of Na+ bile acid cotransport
Ileum
94% are recirculated back to the liver (enterohepatic circulation)
substances must be further digested before it can
be absorbed by specific carriers in intestinal cells?
Sucrose