Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

mrcp 1 > nephro > Flashcards

nephro Flashcards

1
Q

Main benefit of EPO?

A

Improving exercise tolerance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

First line rx for hyperkalemia?

A

Insulin dextrose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hypercalciuria and renal stones prophylaxis?

A

Thiazide diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Idiopathic membranous glomerulonephritis antibodies?

A

A2 antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Diabetic nephropathy stages?

A

Stage 1 - hyperinfiltration
Stage 2 - GFR remains elevated
Stage 3 - microalbuminuria
Stage 4 - persistent proteinuria, HTN,
Stage 5 - renal replacement therapy needed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Biggest complication of nephrotic syndrome?

A

Renal vein thrombosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

ADPKD scan and management?

A

Abdo USS, mx - tolvaptan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Tamsulosin side effects?

A

Dizziness and postural hypotension - alpha-1 adrenergic receptor antagonist is a vasodilator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Anticoag used during plasma exchange? Electrolyte imbalance?

A

Sodium citrate - hypocalcaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tacrolimus side effect?

A

Tremor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Membranoproliferative glomerulonephritis (mesangiocapillary) types?

A

type 1: cryoglobulinaemia, hepatitis C
type 2: partial lipodystrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Alport syndrome inheritance?

A

X linked dominant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Goodpasture’s syndrome antibodies?

A

IgG deposits on renal biopsy
anti-GBM antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ADPKD medication and drug mechanism?

A

Tolvaptan - Vasopressin receptor 2 antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

HIV-associated nephropathy (HIVAN) glomerulonephritis?

A

Focal segmental glomerulosclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Rapidly progressive glomneph antibodies?

A

cANCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Sx of prerenal uraemia?

A

Kidneys hold on to sodium to preserve volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Nephrogenic diabetes insipidus may be caused genetic mutations - most and least common?

A

more common form affects the vasopression (ADH) receptor
less common form results from a mutation in the gene that encodes the aquaporin 2 channel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Most common cause of peritonitis secondary to peritoneal dialysis?

A

Coagulase-negative Staphylococcus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Barter’s syndrome - normotension or hypertension?

21
Q

Mesangium: normal, with no hypercellularity. The capillary walls are thickened. Subepithelial deposits are seen + creates a ‘spike and dome’ appearance?

A

Membranous glom-nephritis

22
Q

Cause of ADH suppression in the posterior pituitary gland?

23
Q

Graft rejection antibody?

24
Q

Eosinophilia and NSAID use?

A

Acute interstitial nephritis

25
Q

Renal stones on x-ray? Cystine and urate/xanthine?

A

Cystine stones: semi-opaque
Urate + xanthine stones: radio-lucent

26
Q

Testicular seminoma marker?

27
Q

Non-seminomas?

A

hCG and AFP

28
Q

What are stag-horn calculi normally composed of?

A

Struvite - (ammonium magnesium phosphate, triple phosphate)

29
Q

Autosomal dominant polycystic kidney disease type 2 is associated with a gene defect in?

30
Q

CKD on haemodialysis - most likely cause of death?

31
Q

Alport syndrome inheritance?

A

X linked dom

32
Q

Safe drug for SLE in pregnancy?

A

Azathioprine

33
Q

Glomneph in SLE?

A

Diffuse proliferative glomerulonephritis

34
Q

Glomneph associated with cancer?

A

Membranous

35
Q

A 23-year-old man with end-stage renal failure secondary to minimal change disease has presented to the renal clinic along with his brother. They are both undergoing investigation for possible organ donation.

Bloods taken for HLA matching show that antigens A, B, DP, DQ, and DR are matches.

Which is the most important to match?

A

Renal transplant HLA matching - DR is the most important

36
Q

Which glomerulonephritis is most characteristically associated with partial lipodystrophy?

A

Mesangiocapillary glomerulonephritis (membranoproliferative)
T1 - cryoglobulinaemia, hepatitis C
T2 - partial lipodystrop

37
Q

Diabetes insipidus in patients taking lithium mechanism?

A

Lithium desensitises the kidney’s ability to respond to ADH in the collecting ducts

38
Q

Contrast-induced nephropathy occurs when?

A

2 -5 days after administration

39
Q

Proteus mirabilis infection predisposes to which type of stone?

A

Proteus mirabilis infection predisposes to struvite kidney stones

40
Q

Which type of glomerulonephritis is associated with normal complement levels?

A

Goodpasture’s

41
Q

Calcium resonium mechanism of action?

A

Increases K excretion - resonium removes!

42
Q

Membranoproliferative glomerulonephritis secondary to partial lipodystrophy - which complement will be low?

43
Q

eGFR variables?

A

CAGE - creatinine, age, gender, ethnicity

44
Q

Time taken for an arteriovenous fistula to develop?

45
Q

Patients who have received an organ transplant are at risk of skin cancer - which type?

A

Squamous cell cancer

47
Q

How to tell if blood in urine is glomerular in origin?

A

Dysmorphic RBCs on microscopy

49
Q

GFR ACD?

A

zona glom - aldosterone
zona fas - cortisol
zona ret - DHEA

mrcp 1 (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions